Protein Alignment Ctsc and CG5367

DIOPT Version :9

• Sequence 1: NP_034112.3
• Gene: Ctsc / 13032
• MGIID: 109553
• Length: 462
• Species: Mus musculus
• Sequence 2: NP_609387.1
• Gene: CG5367 / 34401
• FlyBaseID: FBgn0032228
• Length: 338
• Species: Drosophila melanogaster
• Alignment Length: 370
• Identity: 105/370 - (28%)
• Similarity: 164/370 - (44%)
• Gaps: 85/370 - (22%)

Mouse   134 WACFVG---KKVESHIEKVNMNAAHLGGLQERYSERLYTHNHNFVKAINTVQKSWTATAYKEYEK 195
            :.|..|   :.|.|::.:.|.::|:.....|::.      |:|..|.:.|..:..:..|::|..|
  Fly     7 FGCLCGLNCQIVTSNLSEGNSSSANCKSEFEKFK------NNNNRKYLRTYDEMRSYKAFEENFK 65

Mouse   196 MSLRDLIRRSGHSQRIPRPKP---APM-TDEIQQQIL------------------------NLPE 232
            : :.:..:.....|...|.||   |.| ||...:..|                        |:||
  Fly    66 V-IEEHNQNYKEGQTSFRLKPNIFADMSTDGYLKGFLRLLKSNIEDSADNMAEIVGSPLMANVPE 129

Mouse   233 SWDWRNVQGVNYVSPVRNQESCGSCYSF----ASMGMLEARI-RILTNNSQTPILSPQEVVSCSP 292
            |.|||:   ..:::|..||.||||||:|    :.||.:..|. :||:       ||.|::|.||.
  Fly   130 SLDWRS---KGFITPPYNQLSCGSCYAFSIAESIMGQVFKRTGKILS-------LSKQQIVDCSV 184

Mouse   293 Y--AQGCDGG-----FPYLIAGKYAQDFGVVEESCFPYTAKDSPCK--PRENCLRYYSSDYYYVG 348
            .  .|||.||     ..||     ....|::.:..:||.|:...|:  |..:.:...|.....|.
  Fly   185 SHGNQGCVGGSLRNTLSYL-----QSTGGIMRDQDYPYVARKGKCQFVPDLSVVNVTSWAILPVR 244

Mouse   349 GFYGGCNEALMKLELVKHGPMAVAFEVH-DDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYG 412
                  :|..::..:...||:|::.... ..|..|..|||     .||.......|||::::|:|
  Fly   245 ------DEQAIQAAVTHIGPVAISINASPKTFQLYSDGIY-----DDPLCSSASVNHAMVVIGFG 298

Mouse   413 RDPVTGIEYWIIKNSWGSNWGESGYFRIRRGTDECAIESIAVAAI 457
            :|      |||:||.||.||||:||.|||:|.:.|.|.:.|..||
  Fly   299 KD------YWILKNWWGQNWGENGYIRIRKGVNMCGIANYAAYAI 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctsc	NP_034112.3	CathepsinC_exc	26..138	CDD:285926	1/3 (33%)
		Pox_I6	168..>204	CDD:252691	7/35 (20%)
		Peptidase_C1A_CathepsinC	230..459	CDD:239112	81/243 (33%)
CG5367	NP_609387.1	Inhibitor_I29	36..96	CDD:285458	16/66 (24%)
		Peptidase_C1A	128..336	CDD:239068	79/239 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820