DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ctla2a and CG5367

DIOPT Version :9

Sequence 1:	NP_031822.2	Gene:	Ctla2a / 13024	MGIID:	88554	Length:	137	Species:	Mus musculus
Sequence 2:	NP_609387.1	Gene:	CG5367 / 34401	FlyBaseID:	FBgn0032228	Length:	338	Species:	Drosophila melanogaster

Alignment Length:	109	Identity:	31/109 - (28%)
Similarity:	54/109 - (49%)	Gaps:	21/109 - (19%)

- Green bases have known domain annotations that are detailed below.

Mouse    44 KTKFAKAYNLNEERHRRL--------VWEENKKKIEAHNADYEQGKTSFYMGLNQFSDLTPEEF- 99
            |::|.|..|.|..::.|.        .:|||.|.||.||.:|::|:|||.:..|.|:|::.:.:
  Fly    33 KSEFEKFKNNNNRKYLRTYDEMRSYKAFEENFKVIEEHNQNYKEGQTSFRLKPNIFADMSTDGYL 97

Mouse   100 -------KTNCYGNSLNRGE-----MAPDLPEYEDLGKNSYLTP 131
                   |:|...::.|..|     :..::||..|.....::||
  Fly    98 KGFLRLLKSNIEDSADNMAEIVGSPLMANVPESLDWRSKGFITP 141

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ctla2a	NP_031822.2	2 X 3 AA tandem repeats of E-W-K	39..44		31/109 (28%)
		Inhibitor_I29	40..98	CDD:214853	22/61 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	114..137		5/18 (28%)
CG5367	NP_609387.1	Inhibitor_I29	36..96	CDD:285458	21/59 (36%)
CG5367	NP_609387.1	Peptidase_C1A	128..336	CDD:239068	5/14 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810