Protein Alignment ADH6 and Drat

DIOPT Version :10

• Sequence 1: NP_001095940.1
• Gene: ADH6 / 130
• HGNCID: 255
• Length: 375
• Species: Homo sapiens
• Sequence 2: NP_610293.3
• Gene: Drat / 35687
• FlyBaseID: FBgn0033188
• Length: 434
• Species: Drosophila melanogaster
• Alignment Length: 310
• Identity: 58/310 - (18%)
• Similarity: 92/310 - (29%)
• Gaps: 110/310 - (35%)

Human    18 PGAPFSIEE--VEVAPPKAKEVRIKVVATGLCG---------TEMKVLGSKHLDL---------- 61
            |||...:..  |.:....|...||::|..|.|.         |.|..:.|:..|.
  Fly    68 PGAKNCVFNFFVPIEDTPALGARIRIVCAGACYRRRDRANSITSMSSVSSELSDYCPSVNSMSSP 132

Human    62 ---------LYPTILGHEGAGIVESIGEGVST-----VKPGDKVITLFLPQCGECTSCLNSEGNF 112
                     .:|   |.|.||::||:|..::.     ::.|.:||
  Fly   133 AHQGIREGSFFP---GFEVAGVIESLGSEITEANNRGLRIGQRVI-------------------- 174

Human   113 CIQFKQSKTQLMSDGTSRFTCKGKSIYHFGNT-STFCEYTVIKEIS-VAKIDAVAPLEKVCLISC 175
                                     :|.|..| :.:.|..|:.::. |..|....|:|...::..
  Fly   175 -------------------------VYPFDETPAGYAELLVVPDLKHVVPIPDSLPMEVAAMLPT 214

Human   176 GFSTGFGAAINTAKVTP------GST-------CAVFGLGGVGLSVV------MGCKAAGAARII 221
            |....:.|......|..      .:|       ..:.|.||:.|..|      .....|....|.
  Fly   215 GALLAWNAVFKAQAVVTQILSQRAATEPKRKPKILIVGTGGLALWAVRIASYHFATTGADNVDIT 279

Human   222 GVDVNKEKFKKAQELGA------TECLNPQDLKKPIQEVLFDMTDAGIDF 265
            ...:..|.|:.|.|:..      .|||....|.:..::|.....|..|||
  Fly   280 VASLRDEGFRLATEIKNVSVVQWNECLYEPQLIERTKDVCGGAVDVVIDF 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ADH6	NP_001095940.1	alcohol_DH_class_I_II_IV	3..375	CDD:176259	58/310 (19%)
Drat	NP_610293.3	MDR	144..428	CDD:450120	44/234 (19%)