Protein Alignment BBS5 and BBS5

DIOPT Version :10

• Sequence 1: NP_689597.1
• Gene: BBS5 / 129880
• HGNCID: 970
• Length: 341
• Species: Homo sapiens
• Sequence 2: NP_649499.1
• Gene: BBS5 / 40600
• FlyBaseID: FBgn0037280
• Length: 381
• Species: Drosophila melanogaster
• Alignment Length: 359
• Identity: 166/359 - (46%)
• Similarity: 235/359 - (65%)
• Gaps: 21/359 - (5%)

Human     3 VLDALWEDRDVRFDLSAQQMKTRPGEVLIDCLDSIEDTKGNNGDRGRLLVTNLRILWHSLALSRV 67
            ||..||||::|:||:.......|.||.::|.:..|||:|||.||.|||:||||||:||||...:.
  Fly    15 VLQLLWEDKEVKFDVPQLHKNLRSGERVLDYIYHIEDSKGNPGDTGRLMVTNLRIIWHSLVHKKY 79

Human    68 NVSVGYNCILNITTRTA--NSKLRGQTEALYILTKCNSTRFEFIFTNLVPGSPR----LFTSVMA 126
            |:|:||..|.|..||..  :||.|..::|||||...|.|||||:||::...:.|    :|.||..
  Fly    80 NLSIGYARIGNTNTRVVHMHSKARIASQALYILAVSNETRFEFLFTDVSGETSRRDQPIFASVFD 144

Human   127 VHRAYETSKMYRDFKLRSALIQNKQLRLLPQEHVYDKINGVWNLSSDQGNLGTFFITNVRIVWHA 191
            |:..|:.:.:|||.|||.|::|..||.:||.|.|:..:.|||||||||||||:|.:||:|:||.|
  Fly   145 VYHLYQRTYLYRDLKLRGAIVQAGQLVILPDEEVFSHVQGVWNLSSDQGNLGSFVVTNIRLVWFA 209

Human   192 NMNDSFNVSIPYLQIRSIKIRDSKFGLALVIESSQQSGGYVLGFKIDPVEKLQESVKEINSLHKV 256
            :.|::||:|:|||||.|:::|:||:|.||||::::..|||||||::||.|:|.|..||::|||.|
  Fly   210 DANETFNISLPYLQIESLRVRESKYGPALVIQTAETGGGYVLGFRVDPAERLNELFKELSSLHTV 274

Human   257 YSASPIFGVDYEMEEKPQPLEALTVEQIQ-DDVEIDSDGHTD---------AFVAYFADG----- 306
            |...|.||:.|...:..:.|||.:.|..| ..:::|:....|         ...:|.|:|
  Fly   275 YGEHPNFGIQYNANDARRRLEAASEEAAQASQIKVDNFEELDERQEREINTKLNSYLAEGCLGKV 339

Human   307 NKQQDREPVFSEELGLAIEKLKDGFTLQGLWEVM 340
            ..|.:|.||:.:|||.|:|.:.||:.||.||.||
  Fly   340 PSQGERAPVYCKELGFAMEPIGDGYKLQDLWNVM 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BBS5	NP_689597.1	BBL5	7..339	CDD:462136	162/352 (46%)
BBS5	NP_649499.1	BBL5	19..372	CDD:462136	164/355 (46%)