Protein Alignment RBM45 and CG1316

DIOPT Version :9

• Sequence 1: XP_016858809.1
• Gene: RBM45 / 129831
• HGNCID: 24468
• Length: 617
• Species: Homo sapiens
• Sequence 2: NP_647887.1
• Gene: CG1316 / 38526
• FlyBaseID: FBgn0035526
• Length: 470
• Species: Drosophila melanogaster
• Alignment Length: 643
• Identity: 181/643 - (28%)
• Similarity: 271/643 - (42%)
• Gaps: 233/643 - (36%)

Human     2 DEAGSSASGGGFRPGVD--SLDEPPNSRIFLVISKYTPESVLRERFSPFGDIQDIWVVRDKHTKE 64
            |....|.|||| |.|.:  :.|:||.||:|::.:|...|...||.|||:|:|:|||||:||||:|
  Fly     3 DYRSQSRSGGG-RGGQEYSNDDDPPMSRLFIICNKAHTEEDFREAFSPYGEIEDIWVVKDKHTQE 66

Human    65 SKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVRVPGSGCPRGKEWASWTSLHLLLCRGEG 129
            :||||:|||:::|.|.:|.|||:|:.:|
  Fly    67 NKGIAYVKFSKTSDAAKAQEEMNGKTIG------------------------------------- 94

Human   130 GVEHPFPAADQTAPGLGTGAALRRGSPPTKLRRVAGKGTGCGVFAPRERTRQPRPPGDRTAVAGL 194
                                         |:                          |||.
  Fly    95 -----------------------------KM--------------------------DRTL---- 100

Human   195 PLSLALTNPPALEFTAKLVLAYFEYFSDLPLSDAQISIYKKRKNSTFPQVFIAQSRSSGSHR-DV 258
                                                            :|.:|.:|:.||:: :.
  Fly   101 ------------------------------------------------KVLVAANRNQGSNKSEN 117

Human   259 EDEELTRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIEN 323
            |.|:..|:|::|||:.||||:||:|..:||:|..:|:|.|..|..||.||||:.|...||.|.||
  Fly   118 EQEKYVRLFIVIPKTATEEDIREEFSQWGDVESVTIVKEKNNGNPKGFGYVRFTKFYYAAVAFEN 182

Human   324 CDRSFRAILAEPKNKASESSEQDYYSNMRQEALGHEPRVNMFPFEQQSEFSSFDKNDSR------ 382
            |...::|:.|||  |.|..:::|.|..               |.|....:||..:.:|.
  Fly   183 CSAKYKAVFAEP--KGSTRTQRDQYGR---------------PSEDNPLYSSSGRGNSNFNGGGS 230

Human   383 -----GQEAISKRLSV-----------VSRVP--------------FTEEQLFSIFDIVPGLEYC 417
                 |..:.:...:|           :..||              ..::||:.:|||:|||:||
  Fly   231 SSGGGGSNSYNNDWNVSQNNDMAAFLRMQNVPVAQPSCLEVNVSNCVNQDQLWRLFDIIPGLDYC 295

Human   418 EVQRDPYSNYGHGVVQYFNVASAIYAKYKLHGFQYPPGNRIGVSFIDDGSNATDLLRKMATQMVA 482
            ::.|:........:|.|.|..:|||||.||||.:||.|.||.|. ::..|:|     :|.|..:.
  Fly   296 QIMREHGPRTNEALVVYDNPEAAIYAKDKLHGLEYPMGERIIVK-VNGMSSA-----RMDTSFID 354

Human   483 AQL-ASMVWNNPSQQQFMQFGGSSGSQLPQIQTDVVLPSCKKKAPAETPVKERLFIVFNPHPLPL 546
            .:. ...:.|.|                        ||..:..|..:..|.:|||||.:.: ||.
  Fly   355 KRTKKDAICNVP------------------------LPPTQPLASPDDQVAQRLFIVLSAN-LPH 394

Human   547 DVLEDIFCRFGNLIEVYLVSGKNVGYAKYADRISANDAIATLHGKILNGVRLKVMLAD 604
            .:|::||..:..||:|||:..||.||.|||:..||..||.||:|..:.|.::|||.|:
  Fly   395 SILKNIFSCWSGLIDVYLLPNKNCGYVKYAEVESAQLAIRTLNGAEICGTKIKVMEAE 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RBM45	XP_016858809.1	RRM1_RBM45	23..101	CDD:409801	39/77 (51%)
		PABP-1234	<41..206	CDD:130689	36/164 (22%)
		RRM2_RBM45	263..336	CDD:409802	35/72 (49%)
		RRM3_RBM45	389..461	CDD:409803	31/96 (32%)
		RRM4_RBM45	534..601	CDD:409804	31/66 (47%)
CG1316	NP_647887.1	RRM1_RBM45	25..105	CDD:240812	44/223 (20%)
		RRM2_RBM45	122..195	CDD:240813	36/74 (49%)
		RRM3_RBM45	267..339	CDD:240814	28/71 (39%)
		RRM4_RBM45	383..449	CDD:240815	31/66 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145844
Domainoid	1	1.000	79	1.000	Domainoid score	I8716
eggNOG	1	0.900	-	-		E1_2CAJT
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15560
Inparanoid	1	1.050	275	1.000	Inparanoid score	I2977
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48842
OrthoDB	1	1.010	-	-		D299261at33208
OrthoFinder	1	1.000	-	-		FOG0007975
OrthoInspector	1	1.000	-	-		oto91200
orthoMCL	1	0.900	-	-		OOG6_108069
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5751
SonicParanoid	1	1.000	-	-		X5918
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.700