Protein Alignment TMEM18 and Tmem18

DIOPT Version :10

• Sequence 1: NP_001339610.1
• Gene: TMEM18 / 129787
• HGNCID: 25257
• Length: 143
• Species: Homo sapiens
• Sequence 2: NP_742046.2
• Gene: Tmem18 / 211986
• MGIID: 2387176
• Length: 140
• Species: Mus musculus
• Alignment Length: 123
• Identity: 95/123 - (77%)
• Similarity: 110/123 - (89%)
• Gaps: 0/123 - (0%)

Human    21 LLQTDWTEPWLMGLATFHALCVLLTCLSSRSYRLQIGHFLCLVILVYCAEYINEAAAMNWRLFSK 85
            :::||||||||:||..||.||:||||.||:.|:||||||||||:|||.||||||.||:|||||||
Mouse    18 IMETDWTEPWLLGLLAFHLLCLLLTCFSSQRYKLQIGHFLCLVVLVYSAEYINEVAAVNWRLFSK 82

Human    86 YQYFDSRGMFISIVFSAPLLVNAMIIVVMWVWKTLNVMTDLKNAQERRKEKKRRRKED 143
            ||||||||||||:|||||||.|||:||:|||.|||.||||||..||.|||::|||||:
Mouse    83 YQYFDSRGMFISLVFSAPLLFNAMLIVIMWVRKTLTVMTDLKTLQEERKERRRRRKEE 140

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMEM18	NP_001339610.1	TMEM18	21..130	CDD:405460	85/108 (79%)
Tmem18	NP_742046.2	TMEM18	16..127	CDD:405460	85/108 (79%)
		DNA-binding. /evidence=ECO:0000250	113..140		19/26 (73%)
		Nuclear localization signal. /evidence=ECO:0000250	130..138		5/7 (71%)