DRSC/TRiP Functional Genomics Resources

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Protein Alignment Csf1r and drpr

DIOPT Version :9

Sequence 1:NP_001032948.2 Gene:Csf1r / 12978 MGIID:1339758 Length:977 Species:Mus musculus
Sequence 2:NP_001261276.1 Gene:drpr / 38218 FlyBaseID:FBgn0027594 Length:1042 Species:Drosophila melanogaster


Alignment Length:363 Identity:73/363 - (20%)
Similarity:113/363 - (31%) Gaps:148/363 - (40%)


- Green bases have known domain annotations that are detailed below.


Mouse   432 CR-GHT-DRCDEAQALQVWNDTHPEVLSQKPFDKVIIQSQLPIGTLKHNMTYFCKTHNSVGNSSQ 494
            || |:| |.|||..|.|                ::..||:                     |||:
  Fly   771 CRSGYTGDNCDELIASQ----------------RIADQSE---------------------NSSR 798

Mouse   495 YFRAVSLGQSKQLPDESLFTPVVVACMSVMSLLVLLLLLLLYKYKQKPKYQVRWKIIERYEGNSY 559
            ...|::|                     |:..|...::..::.|.::....::.:|...:    |
  Fly   799 ASVALTL---------------------VLMTLFACIIFAVFIYYRRRVSNLKTEIAHVH----Y 838

Mouse   560 TF-IDPTQLPYNEKWEFP------------------RNNLQFGKTLG------AGAFGKVVEATA 599
            |. .:|...|.|..::.|                  .||.....|:.      ..|.|:|   .:
  Fly   839 THDTNPPSWPPNHNFDNPVYGMQAETRLLPNNMRSKMNNFDQRSTMSTDYGDDCNASGRV---GS 900

Mouse   600 FGLG-KEDAVLK----------VAVKMLKSTAHADE---KEALMSELKIMSHLGQHENIVNLLGA 650
            :.:. ..|.:.|          |..:.||.....||   ||.....:||.|.:...|:       
  Fly   901 YSINYNHDLLTKNLNADRTNPIVYNESLKEEHVYDEIKHKEGYKDPVKIYSKILFPED------- 958

Mouse   651 CTHGGPVLVITEYCCYGDLLNFLR----------RKAEAMLGPSLSPGQDSEGDSSYKN--IHLE 703
                       ||    |.|::.|          |..:||    |:..||.|..|:.||  :.|.
  Fly   959 -----------EY----DHLDYSRPSTSQKPHYHRMNDAM----LNINQDEEKPSNVKNMTVLLN 1004

Mouse   704 KKYVRRDSGFSSQGVD-TYVEMRPVST---SSSDSFFK 737
            |.....:.....:..| |...:..|||   |||..|.|
  Fly  1005 KPLPPTEPEPQHECFDNTNTNLDNVSTASPSSSPKFLK 1042

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Csf1rNP_001032948.2 ig 25..85 CDD:278476
IG_like 28..101 CDD:214653
IG_like 113..195 CDD:214653
Ig 113..179 CDD:299845
ig 207..293 CDD:278476
IG_like 209..295 CDD:214653
Ig4_SCFR_like 299..398 CDD:143176
IG_like 311..395 CDD:214653
Regulatory juxtamembrane domain. /evidence=ECO:0000250 540..572 6/32 (19%)
PTKc_CSF-1R 541..913 CDD:133237 53/252 (21%)
Pkinase_Tyr 580..904 CDD:285015 44/194 (23%)
Activation loop. /evidence=ECO:0000250 794..816
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 921..957
drprNP_001261276.1 EMI 27..92 CDD:284877
EGF_CA 274..319 CDD:304395
DSL <479..518 CDD:302925
DSL <567..606 CDD:302925
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0200
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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