| Sequence 1: | NP_000085.1 | Gene: | COL7A1 / 1294 | HGNCID: | 2214 | Length: | 2944 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001245581.1 | Gene: | Nrg / 31792 | FlyBaseID: | FBgn0264975 | Length: | 1309 | Species: | Drosophila melanogaster |
| Alignment Length: | 1430 | Identity: | 284/1430 - (19%) |
|---|---|---|---|
| Similarity: | 467/1430 - (32%) | Gaps: | 487/1430 - (34%) |
- Green bases have known domain annotations that are detailed below.
|
Human 5 LLVAALCAGILAE-------------AP-----RVRAQHRERVTCTRLYAADIVFLL----DGSS 47
Human 48 SIGRSNFREVRSF----LEGLVLPFSGAASAQGVRFATVQYSDD-------PRTEFGLDALGSGG 101
Human 102 DVIRAIRELSYKGGNTRTGAAILHVADHVFLPQLARP-GVPKVCILITDGKSQDLVDTAAQRLKG 165
Human 166 QGVKLFAVGIKNADPE------ELKRVASQPTSDFFFFVNDFSILRT--------LLPL------ 210
Human 211 ------------VSRR------------------------------------------------- 214
Human 215 ------------VCTTAGGVP----------------VTRPPDDSTSAPRDLVLSEPSSQSL--- 248
Human 249 RVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEV--------NVPAGETSVRLRGLRPLTEYQV 305
Human 306 TVIALYAN------SIGEAVSGTARTTALEGPELTIQNTTAHS--LLVAW-RSVPGATGYRVTWR 361
Human 362 VLSGGPTQ----------------QQELGPGQ--GSVLLRD-----LEPGTDYEVTVSTLFGRSV 403
Human 404 GPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEARGYRLEWR--RETGLEPPQKVVLPSD- 465
Human 466 -VTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATV----VPTGPELPVSPVTDLQATELPGQRVR 525
Human 526 VSWSPVPGATQYRIIVRSTQGVERTLVL----------------------PGSQTAFDLDDVQAG 568
Human 569 LSYTVRVSA--RVGPREGSASVLTVRREPETPLAVPGLRVVVSDAT---RVRVAWGPVP----GA 624
Human 625 SGFR--ISWSTGSGPESSQTLPP---------DSTATDITGLQPGTTYQVAVSVL----RGREEG 674
Human 675 PAAVIVARTD---PLGPVRTVHVTQ-ASSSSVTITWTRVPGAT------GYRV-SWHSAHGPE-- 726
Human 727 KSQLVSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDV 791
Human 792 LRITWVGVTGATAYRLAW-------GRSEGGPM------------RHQILPGNTDSAEIR----G 833
Human 834 LEGGVSYSVRVTALVGDREGTPVSIVVTTPPEA---PPALGTLHVVQRGEHSLRLRWEPVPRAQG 895
Human 896 ---FLLHWQP----------------EGGQEQSRVLGPELSSY-HLDGLEPATQYRVR-LSVLGP 939
Human 940 AG-EGPSAEVTART-ESPRVPSIELRVVDTSIDS--------VTLAWTPV----------SRASS 984
Human 985 YILSWRPLRGPGQEVPGS------PQTLPGISSS-QRVTGL-EPGV-SYIFSLTPVLDGVRGPEA 1040
Human 1041 SVTQTPVCPRGLADVVFLPHATQDNAHRAEATRRVLERLVLALGPLGPQAVQVGLLSY-SHRPSP 1104
Human 1105 1104 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| COL7A1 | NP_000085.1 | Nonhelical region (NC1) | 17..1253 | 275/1418 (19%) | |
| vWA_collagen_alphaI-XII-like | 37..201 | CDD:238759 | 35/185 (19%) | ||
| fn3 | 233..317 | CDD:278470 | 16/100 (16%) | ||
| fn3 | 333..407 | CDD:278470 | 22/99 (22%) | ||
| fn3 | 426..487 | CDD:278470 | 11/64 (17%) | ||
| fn3 | 509..587 | CDD:278470 | 17/101 (17%) | ||
| FN3 | 598..680 | CDD:238020 | 20/103 (19%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 632..651 | 2/27 (7%) | |||
| FN3 | 687..771 | CDD:238020 | 22/93 (24%) | ||
| fn3 | 779..855 | CDD:278470 | 22/98 (22%) | ||
| FN3 | 867..952 | CDD:238020 | 24/106 (23%) | ||
| FN3 | 955..1044 | CDD:238020 | 21/115 (18%) | ||
| VWA | 1054..1227 | CDD:278519 | 14/52 (27%) | ||
| Cell attachment site. /evidence=ECO:0000255 | 1170..1172 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1239..1941 | ||||
| Triple-helical region | 1254..2784 | ||||
| Interrupted collagenous region | 1254..1477 | ||||
| Collagen | 1299..1353 | CDD:189968 | |||
| Cell attachment site. /evidence=ECO:0000255 | 1334..1336 | ||||
| Collagen | 1451..1504 | CDD:189968 | |||
| Collagen | 1764..1816 | CDD:189968 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1963..2782 | ||||
| Cell attachment site. /evidence=ECO:0000255 | 2008..2010 | ||||
| Collagen | 2022..2074 | CDD:189968 | |||
| Collagen | 2108..2166 | CDD:189968 | |||
| Collagen | 2242..2301 | CDD:189968 | |||
| Collagen | 2324..2369 | CDD:189968 | |||
| Collagen | 2466..2520 | CDD:189968 | |||
| Collagen | 2527..2598 | CDD:189968 | |||
| Cell attachment site. /evidence=ECO:0000255 | 2553..2555 | ||||
| Collagen | 2614..2673 | CDD:189968 | |||
| Collagen | 2650..2707 | CDD:189968 | |||
| Nonhelical region (NC2) | 2785..2944 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2837..2872 | ||||
| KU | 2874..2930 | CDD:238057 | |||
| Nrg | NP_001245581.1 | Ig | 55..128 | CDD:299845 | 14/78 (18%) |
| IG_like | 57..127 | CDD:214653 | 13/75 (17%) | ||
| Ig | 135..214 | CDD:299845 | 19/94 (20%) | ||
| IG_like | 141..216 | CDD:214653 | 18/90 (20%) | ||
| ig | 251..332 | CDD:278476 | 7/80 (9%) | ||
| I-set | 339..427 | CDD:254352 | 17/102 (17%) | ||
| Ig | 354..427 | CDD:299845 | 13/87 (15%) | ||
| I-set | 432..517 | CDD:254352 | 22/89 (25%) | ||
| Ig | 446..517 | CDD:299845 | 18/72 (25%) | ||
| I-set | 522..611 | CDD:254352 | 24/122 (20%) | ||
| ig | 525..609 | CDD:278476 | 24/117 (21%) | ||
| FN3 | 613..707 | CDD:238020 | 22/116 (19%) | ||
| FN3 | 716..807 | CDD:238020 | 19/100 (19%) | ||
| fn3 | 817..905 | CDD:278470 | 20/87 (23%) | ||
| FN3 | 917..1004 | CDD:238020 | 20/96 (21%) | ||
| FN3 | 1041..1111 | CDD:238020 | 17/69 (25%) | ||
| Bravo_FIGEY | 1155..>1221 | CDD:290593 | 16/65 (25%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 0 | 0.000 | |||||