Protein Alignment COL6A2 and col-107

DIOPT Version :10

• Sequence 1: NP_001840.3
• Gene: COL6A2 / 1292
• HGNCID: 2212
• Length: 1019
• Species: Homo sapiens
• Sequence 2: NP_872105.1
• Gene: col-107 / 176961
• WormBaseID: WBGene00000681
• Length: 294
• Species: Caenorhabditis elegans
• Alignment Length: 343
• Identity: 111/343 - (32%)
• Similarity: 137/343 - (39%)
• Gaps: 95/343 - (27%)

Human   201 LRDIASTPHELYRND-YATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIPGPSGPKG-- 262
            |:||         || |..::.|.||. ::|.|            |.:|    ::..|||...
 Worm    29 LQDI---------NDLYYDVMDDMTEF-RNTAN------------EAWK----DMIVPSGAVDAS 67

Human   263 --YRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAG 325
              :...|.:.|..|...:|.          ..|.|..||.|.|         ||.|..|.||.||
 Worm    68 LIFGRNKRSGGTCGCGAQPN----------NCPAGPAGPPGAP---------GAPGEDGTPGQAG 113

Human   326 KNGTDGQKGKLGRIGPPGC----KGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGE 386
            |||.:| .|.:......||    .|:||..|||   |.||:|      |..|.||.||.   .|:
 Worm   114 KNGGNG-IGIVNSADAGGCIKCPAGEPGPAGPD---GPAGAP------GADGQPGAPGN---AGQ 165

Human   387 IGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEG 451
            .||.|:.|.||::||.|..|..||.||||..|.:|                      .|.|||.|
 Worm   166 DGAPGAAGEQGDAGAAGQDGEAGAPGGPGKNGQRG----------------------SGAPGPAG 208

Human   452 PRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFS 516
            |.|.||..|..||.|..|.||..|.:|..|.|||.|..|.|      |..|:.|.:|.||:....
 Worm   209 PEGPAGPAGQDGAPGQDGAPGNAGSEGPAGAPGKDGEAGAP------GQDGEAGGEGIPGQDAAY 267

Human   517 YPGPRGAPGEKGEPGPRG 534
            .|.|......:..|..:|
 Worm   268 CPCPPRTAAVEATPASQG 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
COL6A2	NP_001840.3	Nonhelical region	21..256		13/55 (24%)
		vWA_collagen_alpha_1-VI-type	43..231	CDD:238757	9/30 (30%)
		gly_rich_SclB	<255..>513	CDD:468478	94/265 (35%)
		Triple-helical region	257..590		98/286 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..588		98/286 (34%)
		Cell attachment site. /evidence=ECO:0000255	366..368		0/1 (0%)
		Cell attachment site. /evidence=ECO:0000255	426..428		0/1 (0%)
		Collagen	487..556	CDD:460189	13/48 (27%)
		Cell attachment site. /evidence=ECO:0000255	489..491		0/1 (0%)
		Cell attachment site. /evidence=ECO:0000255	498..500		0/1 (0%)
		Cell attachment site. /evidence=ECO:0000255	539..541
		Nonhelical region	591..1019
		vWA_collagen_alpha_1-VI-type	612..803	CDD:238757
		VWA	833..1007	CDD:459670
col-107	NP_872105.1	Col_cuticle_N	6..57	CDD:198156	13/53 (25%)
		gly_rich_SclB	<105..>264	CDD:468478	78/199 (39%)