DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment COL6A2 and col-88

DIOPT Version :10

Sequence 1:NP_001840.3 Gene:COL6A2 / 1292 HGNCID:2212 Length:1019 Species:Homo sapiens
Sequence 2:NP_497131.1 Gene:col-88 / 175170 WormBaseID:WBGene00000663 Length:302 Species:Caenorhabditis elegans


Alignment Length:190 Identity:82/190 - (43%)
Similarity:102/190 - (53%) Gaps:21/190 - (11%)


- Green bases have known domain annotations that are detailed below.


Human   340 GPPGCKGDPGNRGPDGYPGEAGSPGERG-DQGGKGDP--------GRPGRRGPPGEIGAKGSKGY 395
            ||||..|.||:.|.||..|:||..|:.| .||....|        |.||.:||.|..||.|:   
 Worm    97 GPPGPPGAPGDAGLDGENGQAGPNGQDGAGQGSSQQPSECITCPAGAPGPQGPDGPAGAPGA--- 158

Human   396 QGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGE--KGDPGPEGPRGLAGE 458
            .|.:|:||:||..|..||||.:|..|.||..|.||..|:||.:|.:|.  .|.|||:||.|.||:
 Worm   159 DGQAGSPGAPGQDGQPGGPGAQGDAGAPGNDGTPGQDGAPGQNGQRGNGAAGAPGPQGPAGNAGQ 223

Human   459 VGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGD----PGRPG 514
            .|..||.|.   ||.:|..|..|.||:.|..|:.|:||..|..|:||...:    |.|.|
 Worm   224 AGQPGADGQ---PGAQGSAGIAGAPGQPGKAGEDGEAGENGTDGEPGTDAEYCQCPPRTG 280

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
COL6A2NP_001840.3 Nonhelical region 21..256
vWA_collagen_alpha_1-VI-type 43..231 CDD:238757
gly_rich_SclB <255..>513 CDD:468478 80/187 (43%)
Triple-helical region 257..590 82/190 (43%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 257..588 82/190 (43%)
Cell attachment site. /evidence=ECO:0000255 366..368 1/2 (50%)
Cell attachment site. /evidence=ECO:0000255 426..428 0/1 (0%)
Collagen 487..556 CDD:460189 12/32 (38%)
Cell attachment site. /evidence=ECO:0000255 489..491 0/1 (0%)
Cell attachment site. /evidence=ECO:0000255 498..500 0/1 (0%)
Cell attachment site. /evidence=ECO:0000255 539..541
Nonhelical region 591..1019
vWA_collagen_alpha_1-VI-type 612..803 CDD:238757
VWA 833..1007 CDD:459670
col-88NP_497131.1 Col_cuticle_N 12..57 CDD:460226
gly_rich_SclB <111..>269 CDD:468478 71/163 (44%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.