Protein Alignment TANGO2 and YGR127W

DIOPT Version :10

• Sequence 1: NP_001309070.1
• Gene: TANGO2 / 128989
• HGNCID: 25439
• Length: 369
• Species: Homo sapiens
• Sequence 2: NP_011643.1
• Gene: YGR127W / 853028
• SGDID: S000003359
• Length: 312
• Species: Saccharomyces cerevisiae
• Alignment Length: 350
• Identity: 87/350 - (24%)
• Similarity: 134/350 - (38%)
• Gaps: 104/350 - (29%)

Human    59 HRLILAANRDEFYSRPSKLADFWGNNNEILSGLDM----EEGKEGGTWLGISTRGKLAALTNYL- 118
            :.|||.:|||||.:|.:. |..|.||:.|||..|:    .|.:..|||.||:..||||.:.|..
Yeast    13 YELILISNRDEFLARKTH-ATCWHNNDFILSPYDLAKTSAEKQIFGTWSGINKEGKLATILNLKL 76

Human   119 -QPQLDWQARGRGELVTHFLT---TDVDSLSYLKKVSMEGHLYNG------FNLIAADL------ 167
             ..|.:.::|.||.|...||:   .|.:.....||  .||| |:|      ||....|:
Yeast    77 DNEQNNTKSRSRGLLPFIFLSIHKADFEDWDNYKK--FEGH-YDGLKSTGDFNFFYGDVIKKQYK 138

Human   168 -------------STAKGDVICYYGNRGEPDPIVLTPGTYGLSNALLETPWRKLCFGK----QLF 215
                         ||.:.|:..|         :|::.|.:..|:::....|.|:...:    .|.
Yeast   139 VIDSLGRTFDVLSSTCRKDLDSY---------MVVSNGKFYDSSSIPGQAWEKVKVARDSLENLV 194

Human   216 LEAVERSQALPKDVLIASLLDVLNNEEAQLPDPAIEDQGGEYVQPMLSKYAAVCVRCPGYGTRYC 280
            ||.:|..:    :.:|:|...:.:  ::.||.........:.|.|.::                .
Yeast   195 LENIESDE----EKIISSCFQLAS--KSSLPSTISNPDVLQMVDPNVT----------------M 237

Human   281 STVGAPPPIPCPTSHARGPAKKPSAHSQSQASSSPEWIPELLPCPDA-AAGTNT--IILVDADG- 341
            :|:..||        .|.|.:.....|                .||. ..||.:  ::||..|.
Yeast   238 NTIYVPP--------LRRPPRDDLGAS----------------IPDGDYYGTRSQIVLLVSKDST 278

Human   342 HVTFTERSMMDKDLSHWETRTYEFT 366
            .|||.||.:...|   .:.|.|..|
Yeast   279 RVTFIERVLYSSD---EDVRKYSVT 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TANGO2	NP_001309070.1	TANGO2	60..352	CDD:461729	83/333 (25%)
YGR127W	NP_011643.1	TANGO2	1..289	CDD:461729	83/334 (25%)