Protein Alignment Cpa3 and CG18585

DIOPT Version :9

• Sequence 1: NP_031779.1
• Gene: Cpa3 / 12873
• MGIID: 88479
• Length: 417
• Species: Mus musculus
• Sequence 2: NP_001260213.1
• Gene: CG18585 / 34041
• FlyBaseID: FBgn0031929
• Length: 422
• Species: Drosophila melanogaster
• Alignment Length: 419
• Identity: 136/419 - (32%)
• Similarity: 229/419 - (54%)
• Gaps: 24/419 - (5%)

Mouse     1 MRFFLLMAVIYTTLAIAPV-------HFDREKVFRVKLQNEKHASVLKNLTQ-SIELDFW--YPD 55
            ||...|:|.: ..|..|.:       .:|..:|:::.:||:...:.::.:.: :.:.:.|  |.:
  Fly     1 MRLLWLLATL-VALTSAGILKDSPKERYDNFRVYKLTIQNKIQLAAIEKIGELTKKYNIWKEYDE 64

Mouse    56 AIHDIAVNMTVDFRVSEKESQTIQSTLEQHKIHYEILIHDLQEEIEKQFDVKDEIAGRHSYAKYN 120
            .      :..:|..||..|....|..|:.:.|..|::|.::||.|:::.......:....:.||.
  Fly    65 R------SRQIDIMVSPGELNHFQELLKFNNISSELMIENVQERIDEEQVTPTADSATFGWTKYY 123

Mouse   121 DWDKIVSWTEKMLEKHPEMVSRIKIGSTVEDNPLYVLKIGKKDGERKAIFMDCGIHAREWISPAF 185
            :.::|.:|.:::|..:|.:.....:|.:.|...:..:||..|.| ...||::..|||||||:.|.
  Fly   124 ELEEIEAWLDEILNAYPSVTEEFIVGKSYEGRTIRGIKISHKAG-NPGIFIESNIHAREWITSAS 187

Mouse   186 CQWFVYQATKSYGKNKIMTKLLDRMNFYVLPVFNVDGYIWSWTQDRMWRKNRSRNQNSTCIGTDL 250
            ..||:.|...|  ::..:..|.|..:::::|||||||:.:|..:||||||.|..:..:.|||.|.
  Fly   188 ATWFINQLLTS--EDADVRSLADNYDWHIIPVFNVDGFEYSHKKDRMWRKTRQPHATNACIGADA 250

Mouse   251 NRNFDVSW-DSSPNTNKPCLNVYRGPAPESEKETKAVTNFIRSHLNSIKAYITFHSYSQMLLIPY 314
            |||||..| .::..::.||...:.|..||||.|.||:..::....:.|..||:||||.|.||.||
  Fly   251 NRNFDSYWLQNNGASDNPCSETFAGDNPESEPEAKALVEYLTKIQDQISVYISFHSYGQYLLSPY 315

Mouse   315 GYT-FKLPPNHQDLLKVARIATDAL-STRYETRYIYGPIASTIYKTSGSSLDWVY-DLGIKHTFA 376
            |:| .:.|.|:.|:|.:.:...||: :..|.|.|.||..|..:|..:|:|:|||: :||.|..:.
  Fly   316 GHTNEEFPENYNDILTIGKAFADAIEALPYGTVYQYGSTADVLYVATGTSVDWVFNELGKKIGYT 380

Mouse   377 FELRDKGKSGFLLPESRIKPTCKETMLSV 405
            .|.||||:.||:||..:|.|.|:|.|:.:
  Fly   381 IEYRDKGRYGFILPPVQIIPNCEELMVGM 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cpa3	NP_031779.1	Propep_M14	28..102	CDD:280416	16/76 (21%)
		Peptidase_M14_like	114..413	CDD:299699	112/296 (38%)
CG18585	NP_001260213.1	Propep_M14	34..105	CDD:280416	16/76 (21%)
		M14_CP_A-B_like	122..415	CDD:199844	111/291 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848050
Domainoid	1	1.000	233	1.000	Domainoid score	I2384
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3018
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm8747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.830