Protein Alignment PROKR2 and Octbeta2R

DIOPT Version :9

• Sequence 1: NP_658986.1
• Gene: PROKR2 / 128674
• HGNCID: 15836
• Length: 384
• Species: Homo sapiens
• Sequence 2: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Alignment Length: 438
• Identity: 99/438 - (22%)
• Similarity: 162/438 - (36%)
• Gaps: 112/438 - (25%)

Human     8 TSFTPNFNPPQDH-ASSLSFN-----FSYGDYDLPMDEDEDMTKTRTF-FAAKIVIGIALAGIML 65
            |..|...|..|.. .|.|:||     .|...:....:.|||......: |.|.:::.|.:|.|
  Fly   106 TPATHELNATQPFGGSGLNFNESGAGLSDHHHHQQHNPDEDWLDNIVWVFKAFVMLLIIIAAI-- 168

Human    66 VCGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQLSWEHGHVLCAS 130
             |  ||.:.|.::.|.:|||.:||..:.:||::|.:|||:...|.....|..:  |.....||..
  Fly   169 -C--GNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGR--WNFSPFLCDL 228

Human   131 VNYLRTVSLYVSTNALL---AIAIDRYLAIVHPLK-P-RMNYQTASFLIALVWMVSILIA-IPSA 189
            .|   ::.:|.||.::|   .|::|||.|||.||| | .|..:....::...|:...|:: :|
  Fly   229 WN---SLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWISPALLSFLP-- 288

Human   190 YFATETVLFIVKSQEKIFCGQIW---PVDQQ-----------LYYKSYFLFIFGVEFVGPVVTMT 240
                            ||.|  |   |..||           :..|.|.:....:.|..|...|.
  Fly   289 ----------------IFIG--WYTTPQHQQFVIQNPTQCSFVVNKYYAVISSSISFWIPCTIMI 335

Human   241 LCYARISRE-------LWFK-----------------AVPG---------FQTEQIRK------- 265
            ..|..|.||       |..:                 |:.|         .:.||...
  Fly   336 FTYLAIFREANRQEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHL 400

Human   266 -RLRCRRKTVLVLMCILTAYVLCWAPFY-----GFTIVRDFFPTVFVKEKHYLTAFYVVECIAMS 324
             :::...|....|..|:..::|||.||:     ..|......|.:.|.         ::..|...
  Fly   401 IKMKREHKAARTLGIIMGTFILCWLPFFLWYTLSMTCEECQVPDIVVS---------ILFWIGYF 456

Human   325 NSMINTVCFVTVKNNTMKYFKKMMLLHWRPSQRGSKSSADLDLRTNGV 372
            ||.:|.:.:.....:..:.|:..:|..:....:......|:|:|.:.:
  Fly   457 NSTLNPLIYAYFNRDFREAFRNTLLCLFCNWWKDRHLPLDIDIRRSSL 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PROKR2	NP_658986.1	7tm_4	66..>220	CDD:304433	48/173 (28%)
		7tm_1	70..329	CDD:278431	75/324 (23%)
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	56/207 (27%)
		7tm_1	170..465	CDD:278431	76/328 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910