Protein Alignment PROKR2 and DopEcR

DIOPT Version :9

• Sequence 1: NP_658986.1
• Gene: PROKR2 / 128674
• HGNCID: 15836
• Length: 384
• Species: Homo sapiens
• Sequence 2: NP_001014559.1
• Gene: DopEcR / 38539
• FlyBaseID: FBgn0035538
• Length: 322
• Species: Drosophila melanogaster
• Alignment Length: 314
• Identity: 65/314 - (20%)
• Similarity: 110/314 - (35%)
• Gaps: 95/314 - (30%)

Human    41 EDMTKTRTFFAAKIVIGIALAGIMLVCGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAII 105
            :|.:|......|.:   |::.|:.:|  :.|.:.||....:|....:.|..:.:|||:|.|..::
  Fly     8 QDNSKVEALTKAVL---ISILGVAIV--LSNLLIIATYANFKGPTEVINYYLLSLAIADLLCGLL 67

Human   106 CCPFEMDYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQT- 169
            ..||.:  |......|.:|.::|....||......||....:.|::|||||:..||:    |:|
  Fly    68 VVPFSV--YPALTGEWMYGDIVCRFTGYLEVTLWAVSVYTFMWISVDRYLAVRKPLR----YETV 126

Human   170 -----ASFLIALVWMVSILIAIP------------------------SAYFATETVL-------- 197
                 ....:...|:.:.|:..|                        :||.||..:|
  Fly   127 QTKTRCQCWMVFTWISAALLCCPPILGYSMPIENNMTHICMLDWGNMAAYSATLAILVLGPSLIS 191

Human   198 ------FIVKSQEKIFCGQIWPVDQQLYYKSY--------------FLFIFGVEFV--------- 233
                  :|.....||..|:  |:..:.|..:.              .:|.|.|.::
  Fly   192 IVHNYGYIFVMMRKIRSGE--PIHDKEYATALAENLSNPSHMMSFALVFAFWVSWLPWILLRLYE 254

Human   234 ---GPVVTMTL-----CYARISRELWFKAVPGFQTEQIRKRLR-------CRRK 272
               |.|:..||     .:..|....|...:....:.|.|..||       |:.|
  Fly   255 VVTGDVIQSTLINFAVVWIGILNSFWKILIMTSMSPQFRIALRVFCLTICCKTK 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PROKR2	NP_658986.1	7tm_4	66..>220	CDD:304433	44/197 (22%)
		7tm_1	70..329	CDD:278431	59/285 (21%)
DopEcR	NP_001014559.1	7tm_classA_rhodopsin-like	18..289	CDD:410626	57/283 (20%)
		TM helix 1	18..42	CDD:410626	7/28 (25%)
		TM helix 2	51..73	CDD:410626	8/21 (38%)
		TM helix 3	89..111	CDD:410626	5/21 (24%)
		TM helix 4	134..150	CDD:410626	2/15 (13%)
		TM helix 5	174..197	CDD:410626	5/22 (23%)
		TM helix 6	230..252	CDD:410626	3/21 (14%)
		TM helix 7	264..289	CDD:410626	4/24 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910