Protein Alignment PROKR2 and TrissinR

DIOPT Version :9

• Sequence 1: NP_658986.1
• Gene: PROKR2 / 128674
• HGNCID: 15836
• Length: 384
• Species: Homo sapiens
• Sequence 2: NP_001097092.1
• Gene: TrissinR / 33812
• FlyBaseID: FBgn0085410
• Length: 669
• Species: Drosophila melanogaster
• Alignment Length: 558
• Identity: 100/558 - (17%)
• Similarity: 192/558 - (34%)
• Gaps: 200/558 - (35%)

Human     2 AAQNGNTSFTPNFNPPQDHASSLSFNFSYGDYDLPM-----------------DEDEDMTKTRTF 49
            |:.|..::.:|..|     .||..:...||:....:                 :::||..|...:
  Fly   117 ASANVTSTISPPIN-----GSSTDYILLYGESTTSLVPALTTGLSGDGSGAVIEDEEDAEKASEY 176

Human    50 FAAKI---VIGIALAGIML-VCGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFE 110
            ...:.   :|.|.|..::. .|..||.:.|..:|..::||::||..:||||.:||.|.:.|....
  Fly   177 IFDRTDVRIIFITLYTLVFCCCFFGNLLVILVVTLSRRLRSITNFFLANLAFADFCVGLFCVMQN 241

Human   111 MDYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPL--KPRMNYQTASFL 173
            :..|::.  ||..|..||....::.::|...|...|:.|.::||.|||||:  |..:.......:
  Fly   242 LSIYLIE--SWVFGEFLCRMYQFVHSLSYTASIFILVVICMERYFAIVHPITCKQILTAARLRMV 304

Human   174 IALVWMVSILIAIPSAYFATETV--LFIVKSQEKIFCGQIWPVDQQLYYKSYFLFI-FGVEFVGP 235
            |..||:.|.:.:.|...| ::|:  :.....||:..|    .:|::::.......| |.:.:|.|
  Fly   305 IVTVWITSAVYSTPKFVF-SKTIKNIHTQDGQEEEIC----VLDREMFNSKLLDMINFVLLYVMP 364

Human   236 VVTMTLCYARISRELWFKA---------------------------------------------- 254
            ::.||:.|::|:..||..:
  Fly   365 LLVMTVLYSKIAIALWRSSRGLTPHVVQHQHQQPQQPSCQDIGMGMHNSMYHHHPHHHHHHHQHH 429

Human   255 ----------------------VPG---------------FQTEQIRKR---------------- 266
                                  .||               .|:.:..||
  Fly   430 QLQSAASSAGVVGVGLGGGGGGGPGPSLASGGSSTTSLSRKQSSKYEKRGVSITESQLDNCKVSL 494

Human   267 ----------------------------------------------------LRCRRKTVLVLMC 279
                                                                ||.||..|.:|:.
  Fly   495 EADRPIVSACRKTSFYHHGHAHHQRAGNASVGGGSGGAGAGATHMSHSSSNVLRARRGVVRMLII 559

Human   280 ILTAYVLCWAPFYGFTIVRDFFPTVFVKEKHY---LTAFYVVECIAMSNSMINTVCFVTVKNNTM 341
            .:..:.||..|::...:.: ::...:..:.::   ||....:  :...||.:|.:.:..:..|..
  Fly   560 FVLTFALCNLPYHARKMWQ-YWSRSYRGDSNFNALLTPLTFL--VTYFNSGVNPLLYAFLSRNFR 621

Human   342 KYFKKMMLLHWRPSQRGSKSSADLD-----LRTNGVPT 374
            |..|:::|..|:..:..|.|::.:.     |:|:.:||
  Fly   622 KGMKELLLCSWKKGKGKSSSNSSMHHKRKALQTHSLPT 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PROKR2	NP_658986.1	7tm_4	66..>220	CDD:304433	46/157 (29%)
		7tm_1	70..329	CDD:278431	73/417 (18%)
TrissinR	NP_001097092.1	7tm_4	191..>327	CDD:304433	42/138 (30%)
		7tm_1	201..>385	CDD:278431	55/190 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910