Protein Alignment PROKR2 and CCKLR-17D3

DIOPT Version :9

• Sequence 1: NP_658986.1
• Gene: PROKR2 / 128674
• HGNCID: 15836
• Length: 384
• Species: Homo sapiens
• Sequence 2: NP_001097023.1
• Gene: CCKLR-17D3 / 32864
• FlyBaseID: FBgn0030954
• Length: 584
• Species: Drosophila melanogaster
• Alignment Length: 465
• Identity: 100/465 - (21%)
• Similarity: 176/465 - (37%)
• Gaps: 146/465 - (31%)

Human    17 PQDHASSLSFNFSYGDYDLPMDEDEDMTKTRTFFAAKIVIGIALAGIMLVCGIGNFVFIAALTRY 81
            |.|..:.|:|:........|.......:.|.|.....::...::  |:|...:||.:.|:.|.:.
  Fly    77 PSDLVTELAFSLGTSSSPSPSSTPASSSSTSTGMPVWLIPSYSM--ILLFAVLGNLLVISTLVQN 139

Human    82 KKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNAL 146
            :::|.:||:.:.||||||.|:.::|.|..:...::|...:  |..||....:.:..|:.||:..|
  Fly   140 RRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNFIF--GEFLCKLFQFSQAASVAVSSWTL 202

Human   147 LAIAIDRYLAIVHPLKPRMNYQTASF---LIALVWMVSILIAIPSAYFATETVLFIVKSQEKIF- 207
            :||:.:||.||.|||:.| ::||.|.   :|..:|:..||...|.|.|:.     ::.:....:
  Fly   203 VAISCERYYAICHPLRSR-SWQTISHAYKIIGFIWLGGILCMTPIAVFSQ-----LIPTSRPGYC 261

Human   208 -CGQIWPVDQ--QLYYKSYFLFIFGVEFVGPVVTMTLCYARISRELWFKAV-------------- 255
             |.:.|| ||  :|:|.....|:.   .|.|::.:.:.|..|:|.|:....
  Fly   262 KCREFWP-DQGYELFYNILLDFLL---LVLPLLVLCVAYILITRTLYVGMAKDSGRILQQSLPVS 322

Human   256 ----------PGFQTE------------------------------------------------- 261
                      ||..:.
  Fly   323 ATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEGSAGGGSTNMATTTLTTRPTAPTV 387

Human   262 -----------------QIR------------KRLRCRRKTVLVLMCILTAYVLCWAPFYGF-TI 296
                             .||            |.|..:::.|.:|..::..:.:||.|.|.. |:
  Fly   388 ITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVVKMLFVLVLEFFICWTPLYVINTM 452

Human   297 VRDFFPTVFVKEKHYL--TAFYVVECIAMSNSMIN--TVCFVTVKNNTMKYFKKMML-----LHW 352
            |....|.|:    .|:  ||...::.:|.|:|..|  |.||:...      |::..:     |.|
  Fly   453 VMLIGPVVY----EYVDYTAISFLQLLAYSSSCCNPITYCFMNAS------FRRAFVDTFKGLPW 507

Human   353 RPSQRGSKSS 362
            |   ||:.:|
  Fly   508 R---RGAGAS 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PROKR2	NP_658986.1	7tm_4	66..>220	CDD:304433	50/160 (31%)
		7tm_1	70..329	CDD:278431	80/370 (22%)
CCKLR-17D3	NP_001097023.1	7tm_4	120..>244	CDD:304433	43/128 (34%)
		7tm_1	128..487	CDD:278431	81/374 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910