Protein Alignment PROKR2 and CCKLR-17D1

DIOPT Version :9

• Sequence 1: NP_658986.1
• Gene: PROKR2 / 128674
• HGNCID: 15836
• Length: 384
• Species: Homo sapiens
• Sequence 2: NP_001097021.1
• Gene: CCKLR-17D1 / 32860
• FlyBaseID: FBgn0259231
• Length: 673
• Species: Drosophila melanogaster
• Alignment Length: 540
• Identity: 102/540 - (18%)
• Similarity: 182/540 - (33%)
• Gaps: 206/540 - (38%)

Human    32 DYDLPMDEDEDMTKTRTFFAAKIVIGI-------------------ALAGIMLVCGIGNFVFIAA 77
            |.||.:|.|...|.:.:..|..:.:..                   ..:.|:|...:||.:.:..
  Fly   135 DLDLNLDMDLATTPSSSTLAPAVTVRTPGNRSVVRVSADVPIWVVPCYSAILLCAVVGNLLVVLT 199

Human    78 LTRYKKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQLSWEHGHVLCASVNYLRTVSLYVS 142
            |.:.:::|.:||:.:.||||||.|:.:.|.|..:...::|...:  |.:||..:.:.:..|:.||
  Fly   200 LVQNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIF--GELLCKLIQFAQAASVAVS 262

Human   143 TNALLAIAIDRYLAIVHPLKPRMNYQT---ASFLIALVWMVSILIAIPSAYFATETVLFIVKSQE 204
            :..|:||:.:||.||.|||:.| .:||   |:.:||::|:.|::...|.|.|:.   |.......
  Fly   263 SWTLVAISCERYYAICHPLRSR-TWQTINHANKIIAIIWLGSLVCMTPIAAFSQ---LMPTSRPG 323

Human   205 KIFCGQIWPVDQQLYYKSYFLFIFGVEFVGPVVTMTLCYARISRELWFK---------------- 253
            ...|.:.||.|...|.::|.||:.....|.|::.::..|..|:|.|:..
  Fly   324 LRKCREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVSMRNERAMNFGSSGPEV 388

Human   254 ----------------------------------------------------------------- 253
                                                                             
  Fly   389 TTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYGHCGSKRRLISGGGPC 453

Human   254 ------------AVPGFQTEQIR------------------------------------------ 264
                        :|...:.:||.
  Fly   454 EGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQMQLQQQGYVSDNESRR 518

Human   265 ---------------------KRLRCRRKTVLVLMCILTAYVLCWAPFYGF-TIVRDFFPTVFVK 307
                                 |.|..:::.|.:|..::..:.:||.|.|.. |:.....|||:
  Fly   519 KSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYVINTMTMLLGPTVY-- 581

Human   308 EKHYL--TAFYVVECIAMSNSMIN--TVCFV--TVKNNTMKYFKKMMLLH--------WRPSQRG 358
              .|:  |:...::.:|.|:|..|  |.||:  :.:...:..||.|.:..        ||   |.
  Fly   582 --EYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFKGMRVCERLCAPCCFWR---RR 641

Human   359 SKSSADLDLRTNGVPTTEEV 378
            ||:..:|.:..|.:.....|
  Fly   642 SKNETNLSVAGNSIALANSV 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PROKR2	NP_658986.1	7tm_4	66..>220	CDD:304433	48/156 (31%)
		7tm_1	70..329	CDD:278431	78/420 (19%)
CCKLR-17D1	NP_001097021.1	7tm_4	185..>308	CDD:304433	42/125 (34%)
		7tm_1	192..>380	CDD:278431	58/193 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910