Protein Alignment PROKR2 and mAChR-C

DIOPT Version :9

• Sequence 1: NP_658986.1
• Gene: PROKR2 / 128674
• HGNCID: 15836
• Length: 384
• Species: Homo sapiens
• Sequence 2: NP_572358.1
• Gene: mAChR-C / 31626
• FlyBaseID: FBgn0029909
• Length: 371
• Species: Drosophila melanogaster
• Alignment Length: 407
• Identity: 94/407 - (23%)
• Similarity: 169/407 - (41%)
• Gaps: 80/407 - (19%)

Human     9 SFTPNFNPPQDHASS------LSFNFSYGDYDLPMDEDEDMTKTRTFFAAKIVIGIALAGIM--L 65
            :||.:.:|..|:.||      :.|.:.:.:   ..:...::|...|.|.|..::.:|:...:  |
  Fly     2 AFTSSSSPAWDYRSSPEALGVVPFLWQHQN---ATETPTEITLQATSFGAGHLLWLAINAFLFVL 63

Human    66 VCGIGNFVFIAALTRYKKLRN-LTNLLIANLAISDFLVAIICCPFEMDYYVVRQLSWEHGHVLCA 129
            :.| ||.:.|.|:...:.||: ::||.|.:||:|||.|. :..|:.:.:|:...:....|.  |.
  Fly    64 ILG-GNILTIVAVRTCRHLRSVISNLFILSLAVSDFCVG-LALPYHLVFYMGSDIGAMRGP--CL 124

Human   130 SVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPR--MNYQTASFLIALVWMVSILIAIPSAYFA 192
            ...:|...:..||...|::||:|||:|:|:.|..|  |..:.|..:|...|.:..|:|:...::
  Fly   125 LRFFLLICACCVSMLTLISIAVDRYIAVVYALHYRRYMTRRVAYSIIIFNWCLGALVALLPVFW- 188

Human   193 TETVLFIVKSQEKIFCGQIWPVDQQLYYKSYFL--FIFGVEFVGPV---VTMTLCYARISRELWF 252
                             ..||..|...:.....  :|.||...|.|   :.|.|.|.||.|
  Fly   189 -----------------NRWPDAQACEFDEVLAPGYIAGVITPGFVIIWICMFLVYWRIMR---- 232

Human   253 KAVPGFQTEQIRKRLRCRR---------------------KTVLVLMCILTAYVLCWAPFYGFTI 296
                    |..::.||.|:                     |:|.:::.|:..:.|||.|::...|
  Fly   233 --------EASKQALRLRQSVVYNTDEATTMRNLLLHPDWKSVQIVVFIMGCFTLCWLPYFCVAI 289

Human   297 VRDFFPTVFVKEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTMKYFKKMMLLHWRPSQRGSKS 361
            .: .|.........|.|.|    .:|::||.:|.:.: :.||:..:......|......|...:.
  Fly   290 AQ-LFSICQSSSMIYKTTF----SLAIANSALNPIIY-SWKNSGFRRAFVQTLCCRTARQCEDQL 348

Human   362 SADLDLRTNGVPTTEEV 378
            .||...|.....:::|:
  Fly   349 PADSKHRMEATSSSQEI 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PROKR2	NP_658986.1	7tm_4	66..>220	CDD:304433	42/156 (27%)
		7tm_1	70..329	CDD:278431	71/287 (25%)
mAChR-C	NP_572358.1	7tm_4	61..332	CDD:304433	76/310 (25%)
		7tm_1	67..321	CDD:278431	72/291 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910