Protein Alignment PROKR2 and Prokr2

DIOPT Version :10

• Sequence 1: NP_658986.1
• Gene: PROKR2 / 128674
• HGNCID: 15836
• Length: 384
• Species: Homo sapiens
• Sequence 2: NP_620434.2
• Gene: Prokr2 / 192649
• RGDID: 708445
• Length: 422
• Species: Rattus norvegicus
• Alignment Length: 384
• Identity: 346/384 - (90%)
• Similarity: 368/384 - (95%)
• Gaps: 0/384 - (0%)

Human     1 MAAQNGNTSFTPNFNPPQDHASSLSFNFSYGDYDLPMDEDEDMTKTRTFFAAKIVIGIALAGIML 65
            |..|||||||.|:.||||||.|.|..|:||||||:|:|:|||:|||:||||||||||:|||||||
  Rat    39 MGDQNGNTSFAPDLNPPQDHVSLLPLNYSYGDYDIPLDDDEDVTKTQTFFAAKIVIGVALAGIML 103

Human    66 VCGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQLSWEHGHVLCAS 130
            |||:|||||||||.|||||||||||||||||||||||||:|||||||||||||||||||||||||
  Rat   104 VCGVGNFVFIAALARYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVLCAS 168

Human   131 VNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFLIALVWMVSILIAIPSAYFATET 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.|||
  Rat   169 VNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFLIALVWMVSILIAIPSAYFTTET 233

Human   196 VLFIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGVEFVGPVVTMTLCYARISRELWFKAVPGFQT 260
            :|.|||:|||:||||||||||||||||||||:||:|||||||||||||||||:||||||||||||
  Rat   234 ILVIVKNQEKLFCGQIWPVDQQLYYKSYFLFVFGLEFVGPVVTMTLCYARISQELWFKAVPGFQT 298

Human   261 EQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPTVFVKEKHYLTAFYVVECIAMSN 325
            |||||||||||||||:||.||||||||||||||||||||||||:.||||||||||||||||||||
  Rat   299 EQIRKRLRCRRKTVLLLMGILTAYVLCWAPFYGFTIVRDFFPTLVVKEKHYLTAFYVVECIAMSN 363

Human   326 SMINTVCFVTVKNNTMKYFKKMMLLHWRPSQRGSKSSADLDLRTNGVPTTEEVDCIRLK 384
            |||||:||||||||||||||||:|||||||..||||||||||:|:|||.||||||||||
  Rat   364 SMINTICFVTVKNNTMKYFKKMLLLHWRPSHYGSKSSADLDLKTSGVPATEEVDCIRLK 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PROKR2	NP_658986.1	7tmA_prokineticin-R	54..344	CDD:320332	272/289 (94%)
		TM helix 1	55..81	CDD:320332	22/25 (88%)
		TM helix 2	88..113	CDD:320332	23/24 (96%)
		TM helix 3	128..158	CDD:320332	29/29 (100%)
		TM helix 4	169..190	CDD:320332	20/20 (100%)
		TM helix 5	220..249	CDD:320332	26/28 (93%)
		TM helix 6	268..298	CDD:320332	27/29 (93%)
		TM helix 7	312..337	CDD:320332	23/24 (96%)
Prokr2	NP_620434.2	7tmA_prokineticin-R	92..382	CDD:320332	272/289 (94%)
		TM helix 1	93..119	CDD:320332	22/25 (88%)
		TM helix 2	126..151	CDD:320332	23/24 (96%)
		TM helix 3	166..196	CDD:320332	29/29 (100%)
		TM helix 4	207..228	CDD:320332	20/20 (100%)
		TM helix 5	258..287	CDD:320332	26/28 (93%)
		TM helix 6	306..336	CDD:320332	27/29 (93%)
		TM helix 7	350..375	CDD:320332	23/24 (96%)