Protein Alignment ZNF831 and bcl-11

DIOPT Version :10

• Sequence 1: NP_848552.1
• Gene: ZNF831 / 128611
• HGNCID: 16167
• Length: 1677
• Species: Homo sapiens
• Sequence 2: NP_001122913.1
• Gene: bcl-11 / 179019
• WormBaseID: WBGene00017430
• Length: 694
• Species: Caenorhabditis elegans
• Alignment Length: 335
• Identity: 68/335 - (20%)
• Similarity: 99/335 - (29%)
• Gaps: 137/335 - (40%)

Human     4 PEPTCPAP--------PARDQPAPTPGPPG-APGGQASPHLTLGPVLLPPEQGLAPPTVFLKALP 59
            |:|..|.|        ...|:.:.||.|.. |...:||           ||:.|.||...:|
 Worm   419 PQPPAPTPLFQSLNRLSTADESSYTPRPASVAIRRRAS-----------PEEELTPPRKSMK--- 469

Human    60 IPLYHTVPPGGLQPRAPLVTGSLDGGNVPFILSPVLQPEGPGPTQVGKPAAPTLTVNIVGTLPVL 124
                       ::....|:.  :|.|                  ::.:|||
 Worm   470 -----------IEEEDQLIV--VDDG------------------ELAEPAA-------------- 489

Human   125 SPGLGPTLGSPGKVRNAGKYLCPHCGRDCLKPSVLEKHIRSHTGERPFPCATCGIAFKTQSNLYK 189
                       .|..|..|..|..|.:.....|.|..|:||||||:|:.|..|..|....|.|.:
 Worm   490 -----------RKPNNIKKERCNFCNKVFTNRSNLIVHLRSHTGEKPYKCQLCPYACAQSSKLTR 543

Human   190 HRRT------------------------QTHLNNSRLSSESEGAGGGLLEEGDKAGEPPRPEGRG 230
            |.||                        :.|:....:|::....||...|...:    |.|
 Worm   544 HMRTHGQQGKETYHCYICRMPFSVHSTLEKHMRKCVVSTQGRREGGSPPERSIR----PTP---- 600

Human   231 ESRCQGMHEGASERPLS-PGAHVPLLAKNLDVRTEAAPCPGSAFADREAP--------WDSAPMA 286
                ..:.|..|...|| |...||             |.|.::...:...        |..|..|
 Worm   601 ----SALAEATSLLALSAPSISVP-------------PQPQASTVGQNQSQSHQIVLNWLHALNA 648

Human   287 SPGLPAASTQ 296
            |...|.|:::
 Worm   649 SNSTPTATSK 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZNF831	NP_848552.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43		11/47 (23%)
		C2H2 Zn finger	146..166	CDD:275368	6/19 (32%)
		zf-H2C2_2	159..183	CDD:463886	12/23 (52%)
		C2H2 Zn finger	174..193	CDD:275368	6/18 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	193..250		13/81 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	270..398		6/35 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	516..557
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	663..931
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	950..1062
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1100..1119
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1137..1176
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1216..1243
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1510..1597
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1620..1677
bcl-11	NP_001122913.1	zf-C2H2	499..520	CDD:395048	6/20 (30%)
		C2H2 Zn finger	500..520	CDD:275368	6/19 (32%)
		zf-H2C2_2	512..537	CDD:463886	12/24 (50%)
		C2H2 Zn finger	528..548	CDD:275368	7/19 (37%)
		C2H2 Zn finger	558..576	CDD:275368	1/17 (6%)