Protein Alignment ZNF831 and tra-1

DIOPT Version :10

• Sequence 1: NP_848552.1
• Gene: ZNF831 / 128611
• HGNCID: 16167
• Length: 1677
• Species: Homo sapiens
• Sequence 2: NP_001022880.2
• Gene: tra-1 / 176548
• WormBaseID: WBGene00006604
• Length: 1110
• Species: Caenorhabditis elegans
• Alignment Length: 676
• Identity: 130/676 - (19%)
• Similarity: 198/676 - (29%)
• Gaps: 242/676 - (35%)

Human   136 GKVRNAGKYLCPHCGRDCLKPSVLEKHIRSHTGERPFPC--ATCGIAFKTQSNLYKHRRTQTHLN 198
            |:..|..:|  |.||::..:...|:.|.|:||||:|:.|  |.|..||...|:..|| :.:||.|
 Worm   272 GEKPNKCEY--PGCGKEYSRLENLKTHRRTHTGEKPYKCEFADCEKAFSNASDRAKH-QNRTHSN 333

Human   199 NSRLSSESEGAGGGLLEEGDKAGEPPRPEGRGESRCQGMHEGASERPLSPGAHVPLLAKNL---- 259
            ....|                              ||                :|...|:.
 Worm   334 LKPYS------------------------------CQ----------------IPQCTKSYTDPS 352

Human   260 DVRTEAAPCPGSAFADREAPWDSAPMASPGLPAASTQPWRKLPEQK-SPTAGKPCALQRQQATAA 323
            .:|.......|.         |....|....||..:.  |:.|:.: :|..|           |.
 Worm   353 SLRKHIKAVHGD---------DEYEKAKKSRPANYSN--RRRPDHRLAPPTG-----------AM 395

Human   324 EKPWDAKAPEGRLRKCESTDSGYLSRSDSAEQPHAPCSPLH-------SLSEHSAESE------- 374
            ..|                   ||:..:|.....|. |.:|       :|::|...::
 Worm   396 SHP-------------------YLATPNSGASVVAH-SSVHQQNFINMALAQHHHNAQRAQQLMA 440

Human   375 --GEGGPGPGPGVAGAEPGAREAGLELEKKRLEERIAQLISHNQAVVDDAQLDNVRPRKTGLSKQ 437
              |...|...|..|.|...| :|..:.:.:.|:..:.|......|....||:.:....:....:|
 Worm   441 ATGNVMPMMDPASAAAAAQA-QAHHQAQAQMLQTHMMQQAQIQAAAQMQAQVQHQAAMQAHAMQQ 504

Human   438 ----------GSIDLPTPYTYKDSFHFDIRALEPGRRRAPGPVRSTWTPPDKSRPLFFHSVPTQL 492
                      |:..|.:|::         ..|.|.  |||..:....|||          .||.:
 Worm   505 AQMVLQNNLLGAQSLLSPFS---------PLLPPS--RAPNVMAMLQTPP----------TPTSV 548

Human   493 STTVECVPVTRSNSLPFVEGSRTWLEPREPRDPWSRTQKPLSPRPGPARL---GCRSGLSSTDVP 554
            :...: :..:|:...|.|..      |..|        .||.|.|.||..   ..|..:...:..
 Worm   549 APMFD-IMTSRAPMAPVVSA------PTAP--------APLVPAPVPASPVFDELREQMREVEPL 598

Human   555 SGHPRALVRQAAVEDL-------------PGTPIGDALVPAEDTDAKRTAAREAMAGKGRAGGRK 606
            ....:.......::|:             |.||.|..|:|           |....|.|..||
 Worm   599 QQQQQQEPMDQDLQDIRVDGDSDDEDEEEPRTPSGALLLP-----------RGGNNGDGGFGG-- 650

Human   607 CGQRRLKMFSQEKWQVYGDETFKRIYQKMKASPHGGKKAREVGMGSGA----------ELGFPLQ 661
            .|..|...         |..|     .::.|:|.....:|..|.|...          :|....|
 Worm   651 SGSSRASS---------GSGT-----MELSAAPISQNGSRASGSGERGMRSFLIADILQLAADFQ 701

Human   662 KEAAGSS----GTVPTQDRRT---------PVHEDISAGATPEPWGNPPALEASLVTEPTKHGET 713
            .|...|.    ....|:|.|:         ..|:.|.....|..|.....|. :|..:|
 Worm   702 NERLLSDVLDLAIFDTRDVRSLHNIYQVYIRAHKAIPITRRPLDWNETHQLH-NLYHDP------ 759

Human   714 VARRGDSDRPRVEEAVSSPALGGRDS 739
                    |....|...|||:..||:
 Worm   760 --------RFNRAEHQDSPAIRDRDT 777

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZNF831	NP_848552.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43
		C2H2 Zn finger	146..166	CDD:275368	6/19 (32%)
		zf-H2C2_2	159..183	CDD:463886	13/25 (52%)
		C2H2 Zn finger	174..193	CDD:275368	8/20 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	193..250		6/56 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	270..398		26/144 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	516..557		9/43 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	663..931		19/90 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	950..1062
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1100..1119
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1137..1176
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1216..1243
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1510..1597
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1620..1677
tra-1	NP_001022880.2	COG5048	<177..358	CDD:227381	31/134 (23%)
		C2H2 Zn finger	246..270	CDD:275368
		SFP1	<272..362	CDD:227516	31/138 (22%)
		C2H2 Zn finger	278..300	CDD:275368	7/23 (30%)
		zf-H2C2_2	292..319	CDD:463886	13/26 (50%)
		C2H2 Zn finger	308..331	CDD:275368	8/23 (35%)
		C2H2 Zn finger	339..362	CDD:275368	5/38 (13%)