|
Human 24 PGAPGGQASPHLTLGPVLLPPEQGLAPPTVFLKALPIPLYHTVPPGGLQPRAPLVTG----SLDG 84
|.|....||...:..|. ..:|::|..||||||.:|||.....|.:||...|.|| |:|.
Frog 14 PWATSAAASDISSKHPA---ENEGVSPQAVFLKALTVPLYQLAQQGNIQPSFQLATGGQGLSVDS 75
Human 85 GNVPFILSPVLQPEGPGPTQVGKPAAPTLTVNIVGTLPVLSPGLGPTL-GSP-GKVRNAGKYLCP 147
.||..|::| ..||......|||||:.|:.|||||.|...|.: ||| .|.:||||::||
Frog 76 SNVSLIINP------HTPTVTQNSPAPTLTLKILNTLPVLQPNSSPIVAGSPLSKSKNAGKHICP 134
Human 148 HCGRDCLKPSVLEKHIRSHTGERPFPCATCGIAFKTQSNLYKHRRTQTHLNNSRLSSESEGAGGG 212
|||||||||||||||||||||||||||.||||:|||||||||||:||||:|||::|.:|: .|.
Frog 135 HCGRDCLKPSVLEKHIRSHTGERPFPCTTCGISFKTQSNLYKHRKTQTHVNNSKMSHDSD--CGH 197
Human 213 LLEEGDKAGEPPRPEGRGESRCQGMHEGASERPLSPGAHVPLLAKNLDVRTEAAPCPGSAFADRE 277
..:|.....:...|.| ..:.|:.....|| |:|........|..:..|
Frog 198 CQDEKAPQSDVEYPSG-SHNVCREAENNAS-----------------DIRVTMKERIHSLISGNE 244
Human 278 A-PWDSAPMASPGLP-------AASTQPWRK--LPEQKSPTAGKPCALQRQQATAAEKPWDAKAP 332
| |..::||....:| ..||...:| |..|.|||:.|...||:||....:|..|:...
Frog 245 AVPVRASPMTCGKIPEPESSAIVLSTLSNQKGMLKGQSSPTSTKQMYLQKQQEYLVDKQRDSSPS 309
Human 333 EGRLRKCESTDSGYLSRSDSAEQPHAPCSPLHSLSEHSAESEGEGGPGPGPGVAGAEPGAREAGL 397
|.:|:|||||||||||.||||:......||||||||.|.||| .|..||. .|.:.|.
Frog 310 ERKLKKCESTDSGYLSHSDSADLQMFTGSPLHSLSESSVESE-------NPLSAGI--SAADCGD 365
Human 398 ELEKKRLEERIAQLISHNQAVVDDAQLDNVRPRKTGLSKQGSIDLPTPYTYKDSFHFDIRALEPG 462
::.||.|||||:.|||.|:|||||..|||||||||.||||||||||.|||:||||||||::.:..
Frog 366 KMGKKTLEERISLLISQNEAVVDDTHLDNVRPRKTALSKQGSIDLPMPYTFKDSFHFDIKSFDMN 430
Human 463 RRRAP-GPVRSTWTPPDKSRPLFFHSVPTQLSTTVECVPVTRSNSLPFVEGSRTWLEPRE-PRDP 525
|::.. ...:|.:|||||::||||||||||.|||::||.:.|||||..|:..|...:..: ||..
Frog 431 RKKVSLCSAKSIFTPPDKNKPLFFHSVPTQFSTTIDCVTLGRSNSLQLVDSQRVPPDKADIPRHN 495
Human 526 WSRTQKPLSPRPGPARLGCRSGLSSTDVPSGHPRALVRQAAVEDLPGTPIGDALVPAEDTDA--- 587
..:.| ||........|...:...:.|:.|.|||.||||.||::||... |.|..|:
Frog 496 CHKKQ-PLDTSFANLFLSNTAASCTVDLSSSHPRGLVRQIAVDELPQPQ------PCESHDSEEI 553
Human 588 --KRTAAREAMAGKGRAGGRKCGQRRLKMFSQEKWQVYGDETFKRIYQKMKASPHGGKKAREVGM 650
|:|...:..:...::..:|..|::..|||.||||:|||||||::|||:|.: .|.:|
Frog 554 KYKKTTTGDRSSSNSKSINKKGSQKKANMFSHEKWQMYGDETFKKLYQKIKKN-EGMRK------ 611
Human 651 GSGAELGFPLQKEAAGSSGTVPTQDRRTP---VHEDISAGATPEPWGNPPALEASLVTEPTKHGE 712
|..|...| .|.: |.|.| .||.|.....|
Frog 612 ---------------------PKADVSEPEELFHNE-------ENWKN----LASAVKSDECH-- 642
Human 713 TVARRGDSDRPRVEEAVSSPALGGRDSPCSGSRSPLVSPNGRLELGWQMPPAPGPLKGGDV---- 773
:.:||...| .|...||..|. |:|.:||.|.|..:
Frog 643 -------ASQPRPPSA----GLASSDSNVSS----------------QLPGSPGILSGDRIPGES 680
Human 774 --EAPRPV-----WPDPKLEG------GARGVG--------------------DVQETCLWAQTV 805
|...|: .|||..:| |.:.|. |....|| .:|
Frog 681 TTENQLPIEDIQSAPDPSKDGPTLLNSGIKNVASTQNALCGLENENPLRNLQTDTSSACL--DSV 743
Human 806 L--------RWPSRGSGED---------KLPSERKKLKVE---DLHSWKQPEPVSAETPGGP--- 847
| :..|....|| :.||:.||.||| |..:....|.:..|....|
Frog 744 LSKVNDEQGKVTSVSKTEDSKVFIPNSVQSPSKSKKPKVETDKDNSASTINESMKKENLSHPEYQ 808
Human 848 --TQPASLSSQKQDADPGEVPGGSKESARQV--GEPLESSGASLAAASVALKRVGPRDKATPLHP 908
.:..||.|.:.....|.|.........:. |:..:.:.:..:.:|...|.....|.:..:..
Frog 809 NNDKCTSLPSTETTYTKGNVEDIDMNRGHETIDGQSFDENISPSSTSSQTKKTHTSVDYSGKVGT 873
Human 909 AAPAPAEHPSLATPPQAPRVLSALADNAFSPKYLLRL----PQAETPLPLPIPWGPRHSQDSLCS 969
..|..:.|.| |.|. |...:.||||.|.::| ||....|
Frog 874 NIPWKSVHQS--TEPS-----STGKETAFSPSYQIKLQATGPQVIATL----------------- 914
Human 970 SGWPEERASFVGSGLGTPLSPSPASGPSPGEADSILE--DPSCSRPQDGRKGAQLGGD--KGDRM 1030
||:. |:|..:....:.|.|.| |::| |.|....::..|... ||: |...|
Frog 915 ----EEKP---GNGYVSSFEETAAGGLS-----SMMEQRDTSYLADEESEKDHH-GGEAIKVANM 966
Human 1031 ATSRPAARELPISAPGAPREATSSPPTPTCEAHLVQDMEGDSHRIHRLCMGSTLARARLSGDVLN 1095
.||. :..|..|...|..|...| .| .|.:||.:| ||.| .|...
Frog 967 TTSL-----IVSSTQGGWNEVHSCSST-VC-THYLQDRQG---------MGMT-------SDYTV 1008
Human 1096 PW----------VP------------NWE---LGEPPGNAPEDPSSGPLVGPDPCSPL---QPGS 1132
|: || |:| ..|..|...::..|.. ||....|.: :..|
Frog 1009 PFYKGGFFISSEVPCPDQILQLLRTENYEQMSRAEEKGFLEKEMVSED-VGKTSFSFITSSKDQS 1072
Human 1133 FLTALTRPQGVPPGW----------PELALSSHSGTSRSHSTRSPHSTQNPFPSLKAEPRLTWCC 1187
.|..|..|:...|.| .:|.:...:..|.:....:..|.:..|.:|..||:.||||
Frog 1073 SLLHLRDPKTFKPLWNPQAGATTQEQQLPVEKSATVSLALDKYNIQSMKVTFSTLSTEPKPTWCC 1137
Human 1188 LSRSVPLPAEQKAKAASVYLAVHFPGSSLRDEGPNGPPGSNGGWTWTSPGEGGPAQMSKFSYPTV 1252
|:|||||||.|| |.:|||..: |.:|.|
Frog 1138 LNRSVPLPAVQK-KCSSVYSTI-------------------------------PFEMCK------ 1164
Human 1253 PGVMPQHQVSEPEWKKGLPWRAKMSRGNSKQRKLKINPKRYKGNFLQSCV------QLRASRLRT 1311
.|:|..:.....|.::.|......|.|.: :|:.|.|..
Frog 1165 ---------------------GKISGSDPLASSLDVSQKANNNKILDSIINLTGNPELQDSSLTL 1208
Human 1312 PTWVRRRSRHPPALEGLKP--CRTPGQTSSEIAGLNLQEEP----SCATSESPPCCGKEEKKEGD 1370
|:..:: |.|:| |..| .|::....::||. :.|...:........||.|.
Frog 1209 PSCDQK--------ETLEPLGCPFP---HSQLQESRIKEEDHASRALARKGNKTLANIRHKKRGS 1262
Human 1371 C-----RQTLGTLSLGTSSRIVREMDKRTVKDISPSAGEHGDCTTHSTA------------ATSG 1418
. |:..|...|.....:...:.|::......|:..|.| || ||:|
Frog 1263 AIAQGKRRVFGANRLRRCRNVSHHVTKQSHNQKKFSSPSHWD-----TAEGFNKMRPSRRKATAG 1322
Human 1419 LSLQSDTC---LAVVNDVPLPPGKGLDLGLLETQLLASQDSVSTDPKPYIFSDAQRPSSFGSKGT 1480
.| .|.|...|.|..:.:: .|....|.|:.:.| ||..|:|
Frog 1323 ------KCGEQRADVQHRPAPYRQNVE---AEDHGAADQERLKT--------DADVPNS------ 1364
Human 1481 FPHHDIATSVAAVCISLPVRTDHIAQEIHSAESRDHSQTA----GRTLTSSSPDSKVTEEGRAQT 1541
..:...:.:|. ||.:.| |:|:..|...|....:|. ..|.::.|...|..|||.:..
Frog 1365 ---RSVPADIRSVS-SLNLGT-HLAEPTHRVHSELFQKTGLNQKSSTESNDSYTQKGNEEGTSHF 1424
Human 1542 LLPGRPSSGQRISDSVPLESTEKTHL--EIPASGPSSASSHHKEGRHKTFFPS-RGQYGCGEMT- 1602
...| :.||:|:: || .:|.: |.....| |.||...| .||...|.::
Frog 1425 AFLG-----------IKLENTQQ-HLGDALPPN-PIRKVLH----RSKTIGSSLDGQAVPGTLSH 1472
Human 1603 -------------VPCPSLGSDGRKRQVSGLITRKDSVVPSKPEQPIEIPEAP-SKSL------- 1646
|.|.:...:..:.:|:...|.|.|:..|...:...:.|.| |:||
Frog 1473 NITLNDAPRLSHYVDCGTSLCNTHELKVAISPTSKGSIQSSLDSRTSWLKEEPLSQSLADLANPQ 1537
Human 1647 -------KKRSLEGMRKQTRVEFSDTSSDDEDRLVIEI 1677
||.|||.|||||||::||:||||||||||::
Frog 1538 PLLYQSQKKLSLEVMRKQTRVDYSDSSSDDEDRLVIDV 1575
| 
