DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AgaP_AGAP002028 and DMA2

DIOPT Version :9

Sequence 1:	XP_321026.4	Gene:	AgaP_AGAP002028 / 1281089	VectorBaseID:	AGAP002028	Length:	615	Species:	Anopheles gambiae
Sequence 2:	NP_014283.3	Gene:	DMA2 / 855607	SGDID:	S000005060	Length:	522	Species:	Saccharomyces cerevisiae

Alignment Length:	264	Identity:	59/264 - (22%)
Similarity:	91/264 - (34%)	Gaps:	76/264 - (28%)

- Green bases have known domain annotations that are detailed below.

Mosquito   327 STPLLNSTENSTSGSAAGVVTAPPATSSSSPVTAAVAPSGN-SGAGAQTAAAAAP-------QRD 383
            :.|..:.|.||:|.|.|.       |:|||.:......||. |...|:.|:..:.       :::
Yeast    13 TAPTSSMTSNSSSASNAN-------TTSSSGINPRNRASGTPSNERARPASGISSFLNTFGIRQN 70

Mosquito   384 QQQLQQNAAPDSHVMEVPPSDDD----DEMLDDRNVPSARWLLRGRTSSQQQHQQQQQPQQQPL- 443
            .|....:||||..:....||:..    .|.:|              |:.|||..:...|.|.||
Yeast    71 SQTASSSAAPDQRLFGTTPSNSHMSVAMESID--------------TAPQQQEPRLHHPIQMPLS 121

Mosquito   444 -----NESPYSPIGDNVATPSRWRFFQRFFTRSTAQSDT---EGNNIQEPPAPAQAPSPQPFSPT 500
                 :.:...||..::..|:         |....||..   ||||:...........|...:.|
Yeast   122 AQFHVHRNYQLPISISLTAPT---------TTDHQQSSAHNFEGNNVGNVQESLNQRQPNGTNNT 177

Mosquito   501 -------VPLGTGNNILNAHLSGSFHGSEDTTDDE---------LLDAMQRDRTKQRQFRSAPDM 549
                   .|..|..||:     |...||....:.:         :..|.|.:.|:....    |:
Yeast   178 TTSIISMAPAATTRNIV-----GGADGSTIVNNSQEMYKNLRHLIYAANQPNGTEILHL----DL 233

Mosquito   550 PSTS 553
            |:||
Yeast   234 PATS 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AgaP_AGAP002028	XP_321026.4	PA_C_RZF_like	51..197	CDD:239038
AgaP_AGAP002028	XP_321026.4	zf-RING_2	256..300	CDD:290367
DMA2	NP_014283.3	FHA	228..417	CDD:224630	4/14 (29%)
DMA2	NP_014283.3	RING-H2_Dmap_like	431..477	CDD:319372
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X670
TreeFam	0	0.000	Not matched by this tool.
	1	1.000