DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AgaP_AGAP002028 and rnf13

DIOPT Version :9

Sequence 1:	XP_321026.4	Gene:	AgaP_AGAP002028 / 1281089	VectorBaseID:	AGAP002028	Length:	615	Species:	Anopheles gambiae
Sequence 2:	NP_957338.1	Gene:	rnf13 / 793981	ZFINID:	ZDB-GENE-040426-772	Length:	377	Species:	Danio rerio

Alignment Length:	322	Identity:	138/322 - (42%)
Similarity:	194/322 - (60%)	Gaps:	23/322 - (7%)

- Green bases have known domain annotations that are detailed below.

Mosquito    39 VMLVAMVLMLAQPCVRADILVYQMLNDQIIEEFRDLPATFGGEIPDSGLKVLADRADPPDGCTEM 103
            |.:.|.:.:|.   |.|||..|..  |...|.|.||||.||..:|..|||.....|.|.:.|..:
Zfish    21 VQIFAFLNLLP---VEADISAYSF--DNKTENFDDLPARFGYRLPSEGLKGFLIGARPENACVPI 80

Mosquito   104 RPAP---NITSKFAVVIARYNCSFEVKVRNAQQAGYAMVIVHNVGSNDLEHMSANHPQDLL---- 161
            .|.|   |::|.|.|:|.|::|:|::||.:||:|||...|||||.|:||..| .:...|:|
Zfish    81 EPPPQRENLSSAFIVLIRRFDCNFDIKVLHAQKAGYKAAIVHNVDSDDLISM-GSEDLDILKQID 144

Mosquito   162 IPSVFVGESAGRSIIEAYLYDHDYALVITDDIPFNISNNLIIPFAIVVGLCFIIMVLFMIIRCIR 226
            |||||:||.|..|:.|.|:|:....:::..|....:...| |||.|:||:|.|::|:|||.:.::
Zfish   145 IPSVFIGEEAANSLKEDYIYEKGGHVILMPDFSLPLEYYL-IPFLIIVGICLILIVVFMITKFVQ 208

Mosquito   227 ERRRRMRHRLPARVLRKIGIVKFAKGMRFDTCAICLEDFVENERLRVLPCRHAYHAICIDPWLTK 291
            :|.|..|.||....|:|:.|.||.||..:|.|||||:::.|.||||||||.||||..|:||||||
Zfish   209 DRHRARRSRLRKDQLKKLPIHKFKKGDSYDVCAICLDEYEEGERLRVLPCSHAYHCKCVDPWLTK 273

Mosquito   292 NRRVCPICKRRVIVR-GEARQRRYSSDSMSSTNAD----ESTPLLNSTENSTSGSAAGVVTA 348
            .::.||:||::|:.. |::..   .|||:.|...|    |:||||.|.. |||..:.|.::|
Zfish   274 TKKTCPVCKQKVVPSDGDSES---DSDSVDSGGEDNEVSENTPLLRSLA-STSAHSFGSMSA 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AgaP_AGAP002028	XP_321026.4	PA_C_RZF_like	51..197	CDD:239038	62/152 (41%)
AgaP_AGAP002028	XP_321026.4	zf-RING_2	256..300	CDD:290367	28/43 (65%)
rnf13	NP_957338.1	PA_C_RZF_like	23..180	CDD:239038	64/162 (40%)
rnf13	NP_957338.1	zf-RING_2	238..282	CDD:290367	28/43 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	79	1.000	Domainoid score	I8878
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13493
Inparanoid	1	1.050	219	1.000	Inparanoid score	I3662
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0001489
OrthoInspector	1	1.000	-	-		otm39161
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X670
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.970