DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AgaP_AGAP002028 and rnf13

DIOPT Version :9

Sequence 1:	XP_321026.4	Gene:	AgaP_AGAP002028 / 1281089	VectorBaseID:	AGAP002028	Length:	615	Species:	Anopheles gambiae
Sequence 2:	NP_001008015.1	Gene:	rnf13 / 493377	XenbaseID:	XB-GENE-954771	Length:	383	Species:	Xenopus tropicalis

Alignment Length:	420	Identity:	143/420 - (34%)
Similarity:	216/420 - (51%)	Gaps:	81/420 - (19%)

- Green bases have known domain annotations that are detailed below.

Mosquito    53 VRADILVYQMLNDQIIEEFRDLPATFGGEIPDSGLKVLADRADPPDGCTEMRPAP----NITSKF 113
            |:||:..|..  |.:...|.||||.||..:|..|||.....|.|.:.|..:.|.|    |.:|.|
Frog    32 VQADVAAYTA--DNVSRTFDDLPARFGYRLPSDGLKGYIVTAKPENACQPISPPPLLRDNTSSVF 94

Mosquito   114 AVVIARYNCSFEVKVRNAQQAGYAMVIVHNVGSNDLEHMSANHPQDLL----IPSVFVGESAGRS 174
            .|:|.|..|:|::||.|||:||:...:|:||.|:||..|.:| ..|:|    |||||:|||:.|.
Frog    95 IVLIKRLECNFDLKVLNAQKAGFKAAVVYNVDSDDLISMGSN-DVDILKQIDIPSVFIGESSARF 158

Mosquito   175 IIEAYLYDHDYALVITDDIPFNISNNLIIPFAIVVGLCFIIMVLFMIIRCIRERRRRMRHRLPAR 239
            :.|.:.::....:|:..|:...:...| |||.|:||:|.:::|:|||.:.:::|.|..|:||...
Frog   159 LKEEFSWEKGGYIVLVPDLTLPLEYYL-IPFLIIVGICLVLIVIFMITKFVQDRHRARRNRLRKD 222

Mosquito   240 VLRKIGIVKFAKGMRFDTCAICLEDFVENERLRVLPCRHAYHAICIDPWLTKNRRVCPICKRRVI 304
            .|:|:.|.||.||..:|.||:||:::.|.::||:|||.||||..|:||||||.::.||:||::|:
Frog   223 QLKKLPIHKFKKGDEYDVCAVCLDEYEEGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVV 287

Mosquito   305 -VRGEARQRRYSSDSMSSTN-ADESTPLLNSTENSTSGSAAGVVTAPPATSSSSPVTAAVAPSGN 367
             .:|::..   .|||....| ..|:||||.                 |..|:|:
Frog   288 PSQGDSES---DSDSSQEDNEVSENTPLLR-----------------PMASAST----------- 321

Mosquito   368 SGAGAQTAAAAAPQRDQQQLQQNAAPDSHVMEVPPSDDDDEMLDDRNVPSARWLLRGRTSSQQQH 432
                 |:..|.:....||.:.:::..|.       .|||||  ||.:            ||.::|
Frog   322 -----QSFGAISESHSQQNMMESSGEDE-------DDDDDE--DDSD------------SSDEEH 360

Mosquito   433 QQQQQPQQQPLNESPYSPIGDNVATPSRWR 462
            .          .||....:..|:...||.|
Frog   361 N----------TESVVVQLQHNMERESRER 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AgaP_AGAP002028	XP_321026.4	PA_C_RZF_like	51..197	CDD:239038	58/151 (38%)
AgaP_AGAP002028	XP_321026.4	zf-RING_2	256..300	CDD:290367	24/43 (56%)
rnf13	NP_001008015.1	PA_C_RZF_like	24..181	CDD:239038	58/151 (38%)
rnf13	NP_001008015.1	RING_Ubox	239..284	CDD:388418	25/44 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I9141
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H13493
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0001489
OrthoInspector	1	1.000	-	-		otm73799
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X670
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.010