DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AgaP_AGAP002028 and Rnf167

DIOPT Version :9

Sequence 1:	XP_321026.4	Gene:	AgaP_AGAP002028 / 1281089	VectorBaseID:	AGAP002028	Length:	615	Species:	Anopheles gambiae
Sequence 2:	NP_001008362.1	Gene:	Rnf167 / 360554	RGDID:	1305972	Length:	349	Species:	Rattus norvegicus

Alignment Length:	347	Identity:	128/347 - (36%)
Similarity:	190/347 - (54%)	Gaps:	26/347 - (7%)

- Green bases have known domain annotations that are detailed below.

Mosquito    38 LVMLVAMVLMLAQPCVRADILVYQMLNDQIIEEFRDLPATFGGEIPDSGLKVLADRADPPDGCTE 102
            |.::||.||..|.| :|..|......|..:  :|.||||.||..:.|.||:.....|.|.:.|:.
  Rat     8 LPVVVATVLWGAAP-IRGLIRATSEHNASM--DFADLPALFGATLSDEGLQGFLVEAHPENACSP 69

Mosquito   103 MRPAPNIT---SKFAVVIARYNCSFEVKVRNAQQAGYAMVIVHNVGSNDLEHM---SANHPQDLL 161
            :.|.|:..   |.|..::.|::|:|::||.|||:|||...:||||.||:|.:|   |....|.:.
  Rat    70 IAPPPSAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIW 134

Mosquito   162 IPSVFVGESAGRSIIEAYLYDHDYALVITDDIPFNISNNLIIPFAIVVGLCFIIMVLFMIIRCIR 226
            |||||:||.:...:...::|:....:::..|..|.:...| |||..:|||..:.|...:|:|||:
  Rat   135 IPSVFIGERSAEYLRALFVYEKGARVLLVPDNSFPLGYYL-IPFTGIVGLLVLAMGTVLIVRCIQ 198

Mosquito   227 ERRRRMRHRLPARVLRKIGIVKFAKGMRFDTCAICLEDFVENERLRVLPCRHAYHAICIDPWLTK 291
            .|:|..|:||....|::|....:.||..:|.|||||:::.:.::||:|||.||||:.|:|||||:
  Rat   199 HRKRLQRNRLTKEQLKQIPTHDYQKGDEYDVCAICLDEYEDGDKLRILPCAHAYHSRCVDPWLTQ 263

Mosquito   292 NRRVCPICKRRVIVRGEARQRRYSSDSMSSTNADES----------TPLLNS--TENSTSGSAAG 344
            .|:.|||||:.| .||...:.:...........||.          ||||.|  |..::.||.|.
  Rat   264 TRKTCPICKQPV-HRGPGDEEQEEETQGQEEEGDEGEPRDQPASEWTPLLGSSPTLPTSFGSLAP 327

Mosquito   345 ---VVTAPPATSSSSPVTAAVA 363
               |...|....|.||.:||:|
  Rat   328 APLVFPGPSTDPSPSPSSAALA 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AgaP_AGAP002028	XP_321026.4	PA_C_RZF_like	51..197	CDD:239038	52/151 (34%)
AgaP_AGAP002028	XP_321026.4	zf-RING_2	256..300	CDD:290367	25/43 (58%)
Rnf167	NP_001008362.1	PA_C_RZF_like	20..170	CDD:239038	52/152 (34%)
		RING-H2_RNF167	228..273	CDD:319711	26/44 (59%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	271..349		23/78 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I9004
eggNOG	1	0.900	-	-		E1_KOG4628
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I3518
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0001489
OrthoInspector	1	1.000	-	-		otm66479
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X670
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.830