Protein Alignment CG43336 and ACR

DIOPT Version :10

• Sequence 1: NP_001247122.1
• Gene: CG43336 / 12798414
• FlyBaseID: FBgn0263041
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 78/314 - (24%)
• Similarity: 121/314 - (38%)
• Gaps: 86/314 - (27%)

  Fly     9 TFFLLPLLGSTQFLDMA-----CGI--RAHSPSVPRVKNGTVASLTSSPWMA----FLHSTDGRF 62
            |..||.|..|....|.|     ||:  |.:.....|:..|..|...:.|||.    |.:::....
Human     7 TAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYH 71

  Fly    63 ICGGSLITNRLVLTAAHCFLDRTELVARLGEYDREEYEMCHDSYCTYRI---------------- 111
            .|||||:.:|.||||||||:.:..:               ||    :|:
Human    72 TCGGSLLNSRWVLTAAHCFVGKNNV---------------HD----WRLVFGAKEITYGNNKPVK 117

  Fly   112 ----EAMVERGFRHRHYNPMTMAYDIAILRLYRKVQYTDNIRPICIVIDPRWRKYIDSLDPLTGT 172
                |..||:...|..||..|...|||::.:...:.....|.|.|:   |.::..:.     .|:
Human   118 APLQERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCL---PHFKAGLP-----RGS 174

  Fly   173 ------GWGKTESEGD-------SAKLRTVDLARKHPEVCR--RYATLSLTANQFCAGNE--RSN 220
                  |||..|.:..       .|::..:||     ::|.  ::....:.....|||..  :.:
Human   175 QSCWVAGWGYIEEKAPRPSSILMEARVDLIDL-----DLCNSTQWYNGRVQPTNVCAGYPVGKID 234

  Fly   221 LCNGDSGGPVGALIPYGKSKRFVQVGIASFTNTQCVMV---SVFTDVMSYVDWI 271
            .|.||||||:  :....|...:|.|||.|: ...|...   .::|....|::||
Human   235 TCQGDSGGPL--MCKDSKESAYVVVGITSW-GVGCARAKRPGIYTATWPYLNWI 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43336	NP_001247122.1	Tryp_SPc	37..271	CDD:214473	66/277 (24%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	66/277 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421