Protein Alignment CG43335 and TMPRSS5

DIOPT Version :10

• Sequence 1: NP_001247121.1
• Gene: CG43335 / 12798413
• FlyBaseID: FBgn0263040
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_110397.2
• Gene: TMPRSS5 / 80975
• HGNCID: 14908
• Length: 457
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 74/268 - (27%)
• Similarity: 117/268 - (43%)
• Gaps: 50/268 - (18%)

  Fly    29 CGIRTMPSFHRTRIIGGSDAEITSHPWMAYLYNEFHYFCAGTLITNQFVLTAAHCIEASKNLTVR 93
            ||.|.:.|    ||:||........||.|.:...|.:.|.|:::..::|:|||||:.:.:  ..|
Human   209 CGARPLAS----RIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFR--LAR 267

  Fly    94 LGG----------SGLTRSDGSMCQITAEDYSVSMAIKHKYFTPSIMLNDIAMIRLARTVKFYDH 148
            |..          |.:....|::         |...|.|..::......|:|::||...:.|.|.
Human   268 LSSWRVHAGLVSHSAVRPHQGAL---------VERIIPHPLYSAQNHDYDVALLRLQTALNFSDT 323

  Fly   149 IRPICIILDPAVRLLLEDGMTLMATGWGLADKRMHP------HLLQEAPITVMNRNVC--SKLYD 205
            :..:|:   ||.......|.....:|||    ..||      .:||:..:.:.:..:|  |.:|.
Human   324 VGAVCL---PAKEQHFPKGSRCWVSGWG----HTHPSHTYSSDMLQDTVVPLFSTQLCNSSCVYS 381

  Fly   206 VAITQGQICAG--DKETNTCLGDSGGPLGGVVNYYGDL-RFVQYGITSFGD--IECRSPSIYTDL 265
            .|:|...:|||  |...:.|.|||||||   |...||. |.|  |:.|:|.  .|...|.:|..:
Human   382 GALTPRMLCAGYLDGRADACQGDSGGPL---VCPDGDTWRLV--GVVSWGRGCAEPNHPGVYAKV 441

  Fly   266 STYSGWIN 273
            :.:..||:
Human   442 AEFLDWIH 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43335	NP_001247121.1	Tryp_SPc	42..275	CDD:238113	69/255 (27%)
TMPRSS5	NP_110397.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		SRCR_2	116..213	CDD:464747	2/3 (67%)
		Tryp_SPc	217..448	CDD:214473	68/253 (27%)