Protein Alignment CG43335 and KLK10

DIOPT Version :10

• Sequence 1: NP_001247121.1
• Gene: CG43335 / 12798413
• FlyBaseID: FBgn0263040
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_002767.2
• Gene: KLK10 / 5655
• HGNCID: 6358
• Length: 276
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 85/292 - (29%)
• Similarity: 119/292 - (40%)
• Gaps: 55/292 - (18%)

  Fly     4 AAFLVIISVCQWLCRFGESRLLEPNCGIRTMPSFHRTRIIGGSDAEITSHPWMAYLYNEFHYFCA 68
            |..|.::....|.   .|:.|| |....|..|..:      ||.....|.||...|:|...:.||
Human    18 AKLLPLLMAQLWA---AEAALL-PQNDTRLDPEAY------GSPCARGSQPWQVSLFNGLSFHCA 72

  Fly    69 GTLITNQFVLTAAHCIEASKNLTVRLGGSGLTRSDGSMCQITAEDYSVSMAIKHKYFTPSIML-- 131
            |.|:...:|||||||  .:|.|..|:|...|....|...:.|...     .:..||...|..:
Human    73 GVLVDQSWVLTAAHC--GNKPLWARVGDDHLLLLQGEQLRRTTRS-----VVHPKYHQGSGPILP 130

  Fly   132 -----NDIAMIRLARTVKFYDHIRPICIILDPAVRLL------LEDGMTLMATGWGLADKR--MH 183
                 :|:.:::|||.|           :|.|.||.|      .:.|......|||....|  .:
Human   131 RRTDEHDLMLLKLARPV-----------VLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKY 184

  Fly   184 PHLLQEAPITVMNRNVCSKLYDVAITQGQICAG-DKETNTCLGDSGGPLGGVVNYYGDLRFVQYG 247
            ...|..:.||:::...|...|...:|...|||| |:..:.|..||||||  |.:.      ...|
Human   185 NKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQSDSGGPL--VCDE------TLQG 241

  Fly   248 ITSFGDIECRS---PSIYTDLSTYSGWINMVV 276
            |.|:|...|.|   |::||.:..|..|||.|:
Human   242 ILSWGVYPCGSAQHPAVYTQICKYMSWINKVI 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43335	NP_001247121.1	Tryp_SPc	42..275	CDD:238113	75/251 (30%)
KLK10	NP_002767.2	Tryp_SPc	49..272	CDD:238113	75/248 (30%)