Protein Alignment CG43335 and KLK7

DIOPT Version :10

• Sequence 1: NP_001247121.1
• Gene: CG43335 / 12798413
• FlyBaseID: FBgn0263040
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 70/254 - (27%)
• Similarity: 110/254 - (43%)
• Gaps: 43/254 - (16%)

  Fly    41 RIIGGSDAEITSHPWMAYLY--NEFHYFCAGTLITNQFVLTAAHCIEASKNLTVRLGGSGLTRSD 103
            :||.|:.....||||...|.  |:.|  |.|.|:..::|||||||  .....||.||..  |..|
Human    29 KIIDGAPCARGSHPWQVALLSGNQLH--CGGVLVNERWVLTAAHC--KMNEYTVHLGSD--TLGD 87

  Fly   104 GSMCQITAEDYSVSMAIKHKYFTPSIMLNDIAMIRLARTVKFYDHIRPI-----CIILDPAVRLL 163
            ....:|.|     |.:.:|..::....:||:.:::|....:....::.:     |   :|
Human    88 RRAQRIKA-----SKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRC---EP----- 139

  Fly   164 LEDGMTLMATGWGLADKR--MHPHLLQEAPITVMNRNVCSKLYDVAITQGQICAG--DKETNTCL 224
              .|.|...:|||.....  ..|..|....:.:::...|:|:|...:....:|||  |.:.|.|.
Human   140 --PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACN 202

  Fly   225 GDSGGPLGGVVNYYGDLRFVQYGITSFGDIEC---RSPSIYTDLSTYSGWINMVVSQYR 280
            |||||||        ..|....|:.|:|...|   ..|.:||.:..::.|||..:.::|
Human   203 GDSGGPL--------VCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43335	NP_001247121.1	Tryp_SPc	42..275	CDD:238113	69/246 (28%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	66/244 (27%)