Protein Alignment CG43335 and PRSS1

DIOPT Version :10

• Sequence 1: NP_001247121.1
• Gene: CG43335 / 12798413
• FlyBaseID: FBgn0263040
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 72/246 - (29%)
• Similarity: 114/246 - (46%)
• Gaps: 33/246 - (13%)

  Fly    41 RIIGGSDAEITSHPWMAYLYNEFHYFCAGTLITNQFVLTAAHCIEASKNLTVRLGGSGLTRSDGS 105
            :|:||.:.|..|.|:...|.:.:| ||.|:||..|:|::|.||.::  .:.||||...:...:|:
Human    23 KIVGGYNCEENSVPYQVSLNSGYH-FCGGSLINEQWVVSAGHCYKS--RIQVRLGEHNIEVLEGN 84

  Fly   106 MCQITAEDYSVSMAIKHKYFTPSIMLNDIAMIRLARTVKFYDHIRPICIILDPAVRLLLEDGMTL 170
            ...|.|     :..|:|..:....:.|||.:|:|:........:..|.:...|..     .|...
Human    85 EQFINA-----AKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPA-----TGTKC 139

  Fly   171 MATGWGL-----ADKRMHPHLLQEAPITVMNRNVCSKLYDVAITQGQICAGDKE--TNTCLGDSG 228
            :.:|||.     ||   :|..||.....|:::..|...|...||....|.|..|  .::|.||||
Human   140 LISGWGNTASSGAD---YPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSG 201

  Fly   229 GPLGGVVNYYGDLRFVQYGITSFGD--IECRSPSIYTDLSTYSGWINMVVS 277
            ||:  |.|  |.|:    |:.|:||  .:...|.:||.:..|..||...::
Human   202 GPV--VCN--GQLQ----GVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIA 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43335	NP_001247121.1	Tryp_SPc	42..275	CDD:238113	72/241 (30%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	70/239 (29%)