DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43335 and CG3505

DIOPT Version :9

Sequence 1:	NP_001247121.1	Gene:	CG43335 / 12798413	FlyBaseID:	FBgn0263040	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_650380.2	Gene:	CG3505 / 41777	FlyBaseID:	FBgn0038250	Length:	360	Species:	Drosophila melanogaster

Alignment Length:	281	Identity:	80/281 - (28%)
Similarity:	135/281 - (48%)	Gaps:	51/281 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LLEPNCG-IRTMPSFHRTRIIGGSDAEITSHPWMAYL-----YNEFHYFCAGTLITNQFVLTAAH 82
            ||..:|| :|...|       ..:|..|...||:|.:     ..|..:.|.|.||::::||||||
  Fly    95 LLPSDCGKVRWQRS-------NDTDTRIREFPWLALIEYTRGNQEKIHACGGVLISDRYVLTAAH 152

  Fly    83 CI--EASKNL---TVRLGGSGLT-------RSDGSM--CQITAEDYSVSMAIKHKYF--TPSIML 131
            |:  .|:.||   .||||....:       ..|..:  |....:|.::...:.|..:  |....:
  Fly   153 CVAQAATSNLQITAVRLGEWDTSTNPDCQYHEDSKVADCAPPYQDIAIEELLPHPLYNRTDRTQI 217

  Fly   132 NDIAMIRLARTVKFYDHIRPICIILDPAVRLL---LEDGMTLMATGWGLADKRMHPHLLQEAPIT 193
            ||||::|||...|..|.::|||:   |..:|.   |||.:|.:| ||..:..:.    :::..:|
  Fly   218 NDIALVRLASPAKLNDFVQPICL---PNKQLRADELEDLVTEVA-GWQASSSQR----MRKGYVT 274

  Fly   194 VMNRNVCSKLY---DVAITQGQICAGDKETNTCLGDSGGPLGGVVNYYGDLRFVQYGITSFGDIE 255
            :.:...|.:.|   .:.|...::| |...:..|.|::||||   :.:..| .::..|:.|||.:.
  Fly   275 ISSIEECQRKYASQQLRIQASKLC-GLTNSQECYGNAGGPL---MLFKND-GYLLGGLVSFGPVP 334

  Fly   256 CRS---PSIYTDLSTYSGWIN 273
            |.:   |.:||.:::|..||:
  Fly   335 CPNPDWPDVYTRVASYIDWIH 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43335	NP_001247121.1	Tryp_SPc	41..272	CDD:214473	72/260 (28%)
CG43335	NP_001247121.1	Tryp_SPc	42..275	CDD:238113	74/262 (28%)
CG3505	NP_650380.2	CLIP	30..82	CDD:288855
		Tryp_SPc	111..356	CDD:238113	74/258 (29%)
		Tryp_SPc	111..354	CDD:214473	72/255 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463674
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25778
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950