DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG43335 and CG9649

DIOPT Version :9

Sequence 1:	NP_001247121.1	Gene:	CG43335 / 12798413	FlyBaseID:	FBgn0263040	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_650343.1	Gene:	CG9649 / 41727	FlyBaseID:	FBgn0038211	Length:	504	Species:	Drosophila melanogaster

Alignment Length:	287	Identity:	79/287 - (27%)
Similarity:	125/287 - (43%)	Gaps:	77/287 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 CG----IRTMPSFHRTRIIGGSDAEITSHPWMAYLY----NEFHYFCAGTLITNQFVLTAAHCIE 85
            ||    |:| |..|     .|.:.|....||||.|:    .::::.|.||||:.:.|::||||..
  Fly   246 CGREKVIQT-PFIH-----NGIEVERGQLPWMAALFEHVGRDYNFLCGGTLISARTVISAAHCFR 304

  Fly    86 -ASKNL-----TVRLGGSGLTR-SDGSMCQITAEDYSVSMAIKHKYFTPSIMLN-DIAMIRLART 142
             .|:||     .|.||.:.|.. |.|:       ...|:..:.|:.:.|::..: |:|:::|:..
  Fly   305 FGSRNLPGERTIVSLGRNSLDLFSSGA-------TLGVARLLIHEQYNPNVYTDADLALLQLSNH 362

  Fly   143 VKFYDHIRPICIILDPAVRLLLE--DGMTLMATGWGLADKRMHPHLLQEAPITVMNRNV-CSKLY 204
            |...|:|:|||:..:   ..|||  .|......|||..:|.              |||. .:|:.
  Fly   363 VDIGDYIKPICLWNE---NFLLELPSGHKSYVAGWGEDEKG--------------NRNTRLAKMT 410

  Fly   205 DV------------------AITQGQICAGDKE-TNTCLGDSGGPLGGVVNYYGDLRFVQYGITS 250
            |.                  .||...|||.:.: :..|.||||   ||::....|:..:: |:.|
  Fly   411 DTDIITQWECRGNLSEENAKFITSHTICASNAQASGPCSGDSG---GGLMLQEQDIWMLR-GVVS 471

  Fly   251 FGD-----IECRSPSIYTDLSTYSGWI 272
            .|.     .....|.||||::.:..|:
  Fly   472 AGQRMTNRCNLTLPVIYTDVAKHIEWL 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43335	NP_001247121.1	Tryp_SPc	41..272	CDD:214473	72/269 (27%)
CG43335	NP_001247121.1	Tryp_SPc	42..275	CDD:238113	73/270 (27%)
CG9649	NP_650343.1	GD_N	29..124	CDD:292649
		Tryp_SPc	257..498	CDD:238113	73/273 (27%)
		Tryp_SPc	259..497	CDD:214473	72/265 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436591
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940