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Protein Alignment CG43335 and KLKB1

DIOPT Version :10

Sequence 1:	NP_001247121.1	Gene:	CG43335 / 12798413	FlyBaseID:	FBgn0263040	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	XP_011530232.1	Gene:	KLKB1 / 3818	HGNCID:	6371	Length:	649	Species:	Homo sapiens

Alignment Length:	273	Identity:	90/273 - (32%)
Similarity:	134/273 - (49%)	Gaps:	41/273 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LCRFGESRLLEPNCGIRTMPSFHRTRIIGGSDAEITSHPWMAYLYNEF---HYFCAGTLITNQFV 77
            ||..|::.:    |..:|     .|||:||:::.....||...|..:.   .:.|.|:||.:|:|
Human   385 LCNTGDNSV----CTTKT-----STRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWV 440

  Fly    78 LTAAHCIEASKNLTV-RLGGSGLTRSDGSMCQITAED--YSVSMAIKHKYFTPSIMLNDIAMIRL 139
            ||||||.:......| |:....|..||     ||.:.  ..:...|.|:.:..|...:|||:|:|
Human   441 LTAAHCFDGLPLQDVWRIYSGILNLSD-----ITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKL 500

  Fly   140 ARTVKFYDHIRPICIILDPAVRLLLEDGMTL----MATGWGLA-DKRMHPHLLQEAPITVMNRNV 199
            ...:.:.:..:|||:   |:    ..|..|:    ..||||.: :|....::||:..|.::....
Human   501 QAPLNYTEFQKPICL---PS----KGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEE 558

  Fly   200 CSKLY-DVAITQGQICAGDKE--TNTCLGDSGGPLGGVVNYYGDLRFVQYGITSFGDIECR--SP 259
            |.|.| |..|||..:|||.||  .:.|.|||||||  |..:.|..|.|  ||||:|:...|  .|
Human   559 CQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPL--VCKHNGMWRLV--GITSWGEGCARREQP 619

  Fly   260 SIYTDLSTYSGWI 272
            .:||.::.|..||
Human   620 GVYTKVAEYMDWI 632

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.