DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43335 and Sp212

DIOPT Version :9

Sequence 1:	NP_001247121.1	Gene:	CG43335 / 12798413	FlyBaseID:	FBgn0263040	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster

Alignment Length:	255	Identity:	77/255 - (30%)
Similarity:	125/255 - (49%)	Gaps:	42/255 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 IIGGSDAEITSHPWMAYLYNE----FHYFCAGTLITNQFVLTAAHCIE--ASKNLTVRLGGSGLT 100
            |:.|::.....:||::.:|::    ..:.|.|:||::..|::||||:.  ....:.|.||...|.
  Fly   277 IVRGNEFPRGQYPWLSAVYHKEVRALAFKCRGSLISSSIVISAAHCVHRMTEDRVVVGLGRYDLD 341

  Fly   101 --RSDGSMCQITAEDYSVSMAIKH-KYFTPSIMLNDIAMIRLARTVKFYDHIRPICIILDPAVRL 162
              ..||      ||..:|...:.| .|.|.|....|||:|.:.|.|.|.|.|.|||:....|.|.
  Fly   342 DYGEDG------AEMRNVMRLLWHPDYNTRSYSDADIALITIERPVTFNDIIAPICMWTVEASRT 400

  Fly   163 LLEDGMTLMATGWGL---ADKRMHPHLLQEAPITVMNRNVCSKLY-DVAITQGQICAGDKE-TNT 222
            :...|   ...|||.   :.:..:|.:: ||.|.  :..||:..: ...:|:..:|||::: :..
  Fly   401 VSTTG---FIAGWGRDEDSSRTQYPRVV-EAEIA--SPTVCASTWRGTMVTERSLCAGNRDGSGP 459

  Fly   223 CLGDSGGPLGGVVNYYGDLRFVQYGITSFGDIECRSPS---------IYTDLSTYSGWIN 273
            |:||||   ||::...|| |::..||.|.|:   |.|:         :|.|||.:..||:
  Fly   460 CVGDSG---GGLMVKQGD-RWLLRGIVSAGE---RGPAGTCQLNQYVLYCDLSKHINWIS 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43335	NP_001247121.1	Tryp_SPc	41..272	CDD:214473	75/252 (30%)
CG43335	NP_001247121.1	Tryp_SPc	42..275	CDD:238113	77/255 (30%)
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	77/255 (30%)
		Tryp_SPc	277..511	CDD:214473	75/252 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437266
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930