DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43335 and CG30187

DIOPT Version :9

Sequence 1:	NP_001247121.1	Gene:	CG43335 / 12798413	FlyBaseID:	FBgn0263040	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_001246475.2	Gene:	CG30187 / 246509	FlyBaseID:	FBgn0050187	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	97/275 - (35%)
Similarity:	135/275 - (49%)	Gaps:	16/275 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LVIISVCQWLCR-FGESRLLEPNCGIRTMPSFHRTRIIGGSDAEITSHPWMAYLYNEFHYFCAGT 70
            |..|.|..|..: .|.|..|:..|||..     ..:|.||.:|...:..|||.::|..|:.|.||
  Fly     5 LAWIPVIFWFLKDVGASIFLDQICGINI-----ALKITGGHNAAFQNSVWMAAVHNRTHFICGGT 64

  Fly    71 LITNQFVLTAAHCIEASKNLTVRLGGSGLTRSDGSMCQITAEDYSVSMAIKHKYF-TPSIMLNDI 134
            ||..:|||||||||......:|.||  ...:||      .|:...|..|:.|..| ..:...|||
  Fly    65 LIHKRFVLTAAHCIVDQDVQSVSLG--AYNKSD------PADRKDVITAVVHSSFDVRASYENDI 121

  Fly   135 AMIRLARTVKFYDHIRPICIILDPAVRLLLEDGMTLMATGWGLADKRMHPHLLQEAPITVMNRNV 199
            .:::|:..|.|...||||||:|:.::...:.:..|..|.|||.........:||...:..::|..
  Fly   122 GLLKLSSDVIFNALIRPICIVLNKSMANHMRNMRTFKAFGWGTLRGNKTSDILQTIILNHLDREE 186

  Fly   200 CSKLYDVAITQGQICAGDKETNTCLGDSGGPLGGVVNYYG-DLRFVQYGITSFGDIECRSPSIYT 263
            |.....|..::.|||||....:||.|||||||...|...| ..|.||:||.|.|...|....:||
  Fly   187 CYMELSVYPSEKQICAGVPSGDTCGGDSGGPLTNDVFIQGIGNREVQFGIISVGKTSCDGQGVYT 251

  Fly   264 DLSTYSGWINMVVSQ 278
            ||.:::.||.|.:.:
  Fly   252 DLMSFADWIKMTIER 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43335	NP_001247121.1	Tryp_SPc	41..272	CDD:214473	84/232 (36%)
CG43335	NP_001247121.1	Tryp_SPc	42..275	CDD:238113	86/234 (37%)
CG30187	NP_001246475.2	Tryp_SPc	35..260	CDD:214473	84/232 (36%)
CG30187	NP_001246475.2	Trypsin	316..>384	CDD:355628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3480
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.960