Protein Alignment CG43335 and F9

DIOPT Version :10

• Sequence 1: NP_001247121.1
• Gene: CG43335 / 12798413
• FlyBaseID: FBgn0263040
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_000124.1
• Gene: F9 / 2158
• HGNCID: 3551
• Length: 461
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 69/243 - (28%)
• Similarity: 115/243 - (47%)
• Gaps: 23/243 - (9%)

  Fly    40 TRIIGGSDAEITSHPWMAYLYNEFHYFCAGTLITNQFVLTAAHCIEASKNLTVRLGGSGLTRSDG 104
            ||::||.||:....||...|..:...||.|:::..::::|||||:|....:||..|...:..::.
Human   225 TRVVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEETEH 289

  Fly   105 SMCQITAEDYSVSMAIKHKYFTPSI--MLNDIAMIRLARTVKFYDHIRPICIILDPAVRLLLEDG 167
                 |.:..:|...|.|..:..:|  ..:|||::.|...:....::.||||.......:.|:.|
Human   290 -----TEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFG 349

  Fly   168 MTLMATGWG-LADKRMHPHLLQEAPITVMNRNVCSKLYDVAITQGQICAGDKE--TNTCLGDSGG 229
            ...: :||| :..|.....:||...:.:::|..|.:.....|.....|||..|  .::|.|||||
Human   350 SGYV-SGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGG 413

  Fly   230 PLGGVVNYYGDLRFVQY--GITSFGDIECRSP---SIYTDLSTYSGWI 272
            |      :..::....:  ||.|:|: ||...   .|||.:|.|..||
Human   414 P------HVTEVEGTSFLTGIISWGE-ECAMKGKYGIYTKVSRYVNWI 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43335	NP_001247121.1	Tryp_SPc	42..275	CDD:238113	67/241 (28%)
F9	NP_000124.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:464251
		Tryp_SPc	227..457	CDD:238113	67/241 (28%)