Protein Alignment CG43335 and CFD

DIOPT Version :10

• Sequence 1: NP_001247121.1
• Gene: CG43335 / 12798413
• FlyBaseID: FBgn0263040
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 80/259 - (30%)
• Similarity: 126/259 - (48%)
• Gaps: 48/259 - (18%)

  Fly    39 RTRIIGGSDAEITSHPWMAYLYNEFHYFCAGTLITNQFVLTAAHCIE--ASKNLTVRLGGSGLTR 101
            |.||:||.:||..:.|:||.:.....:.|.|.|:..|:||:||||:|  |...:.|.||...|::
Human    30 RGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQ 94

  Fly   102 SDGSMCQITAEDYSVSMAIKHKYFTPSIMLNDIAMIRLARTVKFYDHIRPICIILDPAVRLL--- 163
            .:.|     ...|.|..|:.|....|..:.:|:.:::|:...           .|.||||.|
Human    95 PEPS-----KRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKA-----------TLGPAVRPLPWQ 143

  Fly   164 -----LEDGMTLMATGWGL---ADKRMHPHLLQEAPITVMNRNVCSKL--YDVAITQGQICAGDK 218
                 :..|......|||:   |.:|  |..||...:.|::|..|::.  :|.|||:..:||...
Human   144 RVDRDVAPGTLCDVAGWGIVNHAGRR--PDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESN 206

  Fly   219 ETNTCLGDSGGPL--GGVVNYYGDLRFVQYGITSFGDIEC---RSPSIYTDLSTYSGWINMVVS 277
            ..::|.|||||||  |||:.          |:.:.|...|   :.|.|||.:::|:.||:.|::
Human   207 RRDSCKGDSGGPLVCGGVLE----------GVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43335	NP_001247121.1	Tryp_SPc	42..275	CDD:238113	77/252 (31%)
CFD	NP_001304264.1	Tryp_SPc	33..258	CDD:238113	77/252 (31%)