Protein Alignment CG43335 and KLK8

DIOPT Version :10

• Sequence 1: NP_001247121.1
• Gene: CG43335 / 12798413
• FlyBaseID: FBgn0263040
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 247
• Identity: 74/247 - (29%)
• Similarity: 111/247 - (44%)
• Gaps: 33/247 - (13%)

  Fly    41 RIIGGSDAEITSHPWMAYLYNEFHYFCAGTLITNQFVLTAAHCIEASKNLTVRLGGSGLTRSDGS 105
            :::||.:.:..|.||.|.|:......|.|.|:...:|||||||  .....|||||...|...||
Human    77 KVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHC--KKPKYTVRLGDHSLQNKDG- 138

  Fly   106 MCQITAEDYSVSMAIKHKYFTPSIM---LNDIAMIRLARTVKFYDHIRPICIILDPAVRLLLEDG 167
                ..::..|..:|.|..:..|.:   .:|:.:::|.........::||. :.|...    :.|
Human   139 ----PEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPIS-LADHCT----QPG 194

  Fly   168 MTLMATGWG--LADKRMHPHLLQEAPITVMNRNVCSKLYDVAITQGQICAG-DKETNTCLGDSGG 229
            .....:|||  .:.:...|..|..|.:.:..:..|...|...||.|.:||| .|..:||.|||||
Human   195 QKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGADTCQGDSGG 259

  Fly   230 PL--GGVVNYYGDLRFVQYGITSFGDIEC-RS--PSIYTDLSTYSGWINMVV 276
            ||  .|.:.          ||||:|...| ||  |.:||::..|..||..::
Human   260 PLVCDGALQ----------GITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43335	NP_001247121.1	Tryp_SPc	42..275	CDD:238113	74/243 (30%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	72/241 (30%)