Protein Alignment CG43110 and TMPRSS13

DIOPT Version :10

• Sequence 1: NP_001246396.1
• Gene: CG43110 / 12798330
• FlyBaseID: FBgn0262570
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001070731.1
• Gene: TMPRSS13 / 84000
• HGNCID: 29808
• Length: 567
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 78/260 - (30%)
• Similarity: 124/260 - (47%)
• Gaps: 25/260 - (9%)

  Fly    28 CG-KTPVPKIISGSNASQQSAQYMAGI-FNTTHLLCGGTIIHEDFVLTVAHC------KSTQTLF 84
            || :....:|:.|:.||.....:...: |.||| :||||:|...:|||.|||      |..:...
Human   317 CGLRAMTGRIVGGALASDSKWPWQVSLHFGTTH-ICGGTLIDAQWVLTAAHCFFVTREKVLEGWK 380

  Fly    85 VRLGAYNINHPTDQIRVIETIAHPQYSNSTYANDIALVKLERSVIFNLNIQPICIHLDATLGKQI 149
            |..|..|::...:...:.|.|.:..|::.....||||::|.:.:..:.:|.|.|:.:........
Human   381 VYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLN 445

  Fly   150 RYYNAFGWGRTRNAEQ--SDILQRIFVNRTNPMICHLYLGMSP--DPKQICATTDQG--DTCAGD 208
            ......|:|:||..:.  |..|:.:.||..:...|:.||....  .|:.:||...:|  |:|.||
Human   446 ETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGD 510

  Fly   209 SGGPLISKITYQGKNFDTQFGITSYGT--RECNGVGLYTDVSQYSGWIANIVRSKQDRSVVSRRS 271
            |||||:.    :..|.....|:||:||  .:.|..|:||.|::...||    .||.:..|..|:|
Human   511 SGGPLVC----EQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWI----YSKMESEVRFRKS 567

  Fly   272  271
            Human   568  567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	71/235 (30%)
TMPRSS13	NP_001070731.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..115
		PHA03378	<9..148	CDD:223065
		13 X 5 AA repeats of A-S-P-A-[GLQR]	9..93
		4 X 5 AA repeats of T-P-P-G-R	14..68
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..157
		SRCR_2	231..321	CDD:464747	2/3 (67%)
		Tryp_SPc	325..554	CDD:214473	69/233 (30%)