Protein Alignment CG43110 and PRSS27

DIOPT Version :10

• Sequence 1: NP_001246396.1
• Gene: CG43110 / 12798330
• FlyBaseID: FBgn0262570
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_114154.1
• Gene: PRSS27 / 83886
• HGNCID: 15475
• Length: 290
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 74/260 - (28%)
• Similarity: 119/260 - (45%)
• Gaps: 30/260 - (11%)

  Fly    28 CGK-TPVPKIISGSNASQQSAQYMAGIFNTTHLLCGGTIIHEDFVLTVAHC----KSTQTLFVRL 87
            ||: ..:.:::.|.:..:....:...|.......|||::|.|.:|||.|||    ..|....|.|
Human    26 CGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLL 90

  Fly    88 GAYNINHPTDQ---IRVIETIAHPQYSNSTYANDIALVKLERSVIFNLNIQPICIHLDATLGKQI 149
            ||..:..|...   .||.:..::|.|..:..:.|:|||:||..|.|...|.|:|:...:.:.:..
Human    91 GARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVIFETG 155

  Fly   150 RYYNAFGWGRTRNAE---QSDILQRIFVNRTNPMICHLYLGMSPD----PKQI-----CATTDQG 202
            ......|||.....:   :..|||::.|...:...|:|......:    ||.|     ||..::|
Human   156 MNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEG 220

  Fly   203 --DTCAGDSGGPLISKITYQGKNFDTQFGITSYG---TRECNGVGLYTDVSQYSGWIANIVRSKQ 262
              |.|.|||||||:..:   |::: .|.|:.|:|   .|: |..|:|..|:.:..||..|:...|
Human   221 KKDACKGDSGGPLVCLV---GQSW-LQAGVISWGEGCARQ-NRPGVYIRVTAHHNWIHRIIPKLQ 280

  Fly   263  262
            Human   281  280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	70/244 (29%)
PRSS27	NP_114154.1	Tryp_SPc	36..275	CDD:238113	70/243 (29%)