Protein Alignment CG43110 and Tmprss12

DIOPT Version :10

• Sequence 1: NP_001246396.1
• Gene: CG43110 / 12798330
• FlyBaseID: FBgn0262570
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_898932.2
• Gene: Tmprss12 / 75002
• MGIID: 1922252
• Length: 336
• Species: Mus musculus
• Alignment Length: 309
• Identity: 93/309 - (30%)
• Similarity: 144/309 - (46%)
• Gaps: 64/309 - (20%)

  Fly    25 KQP----CGKTPV------PKIISGSNAS------QQSAQYMAGIFNTTHLLCGGTIIHEDFVLT 73
            :||    ||..|:      .:||.||.|.      |.|.|...|  :....:|||.::.:.:|||
Mouse    45 EQPVTKDCGIAPLRGAVEGSRIIGGSQADTGAWPWQVSLQVQDG--DILMHVCGGALVRDRWVLT 107

  Fly    74 VAHC--KSTQTLFVR--LGAYNIN---HPTDQIRVIETIAHPQYSNSTYANDIALVKLERSVIFN 131
            .|||  ::...|..|  :|..::.   :.:..||:.:.|..|.:...|:.|||||.:|:|:|.:|
Mouse   108 AAHCTKEARDPLKWRAVMGTNDLTRSPYHSRNIRITDIIIPPDFIMETFVNDIALFRLKRAVRYN 172

  Fly   132 LNIQPICI------HLDATLGKQIRYYNAFGWGRTR-NAEQSDILQRIFVNRTNPMICHL---YL 186
            ..|||||:      .||......|.     |||||| ....:.|||...|:..:..:|..   |.
Mouse   173 DYIQPICLPFGVFQKLDQNTACFIS-----GWGRTREEGNGTTILQEAKVHFISREVCSSDQGYS 232

  Fly   187 GMSPDPKQICATTDQG--DTCAGDSGGPLISKITYQGKNFDTQFGITSYGTREC---NGVGLYTD 246
            ||.|: ...||..:.|  |:|.|||||||:..:....:.|  ..|||||| ..|   :..|:|::
Mouse   233 GMIPN-TSFCAGHENGTFDSCRGDSGGPLMCYLPEHSRYF--VMGITSYG-HGCGRRHFPGVYSN 293

  Fly   247 VSQYSGWIANIVRSKQDRSVVSRRSN-----GMFLYSDCTGDSIGSILM 290
            .|.:..|:.:.:    .:..::|..|     |..|      .::||:::
Mouse   294 PSFFQEWMTHYL----SQGNINRLFNMDIVLGQVL------TALGSVIL 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	82/248 (33%)
Tmprss12	NP_898932.2	Tryp_SPc	66..300	CDD:238113	81/244 (33%)