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Protein Alignment CG43110 and TMPRSS4

DIOPT Version :10

Sequence 1:	NP_001246396.1	Gene:	CG43110 / 12798330	FlyBaseID:	FBgn0262570	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	XP_005271670.1	Gene:	TMPRSS4 / 56649	HGNCID:	11878	Length:	494	Species:	Homo sapiens

Alignment Length:	308	Identity:	99/308 - (32%)
Similarity:	144/308 - (46%)	Gaps:	53/308 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 CGKT-PVPKIISGSNASQQSAQYMAGIFNTTHLLCGGTIIHEDFVLTVAHCKSTQT-LF---VRL 87
            |||: ..|:::....||..|..:...|......:|||:|:...:|||.|||....| :|   ||.
Human   196 CGKSLKTPRVVGVEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRA 260

  Fly    88 GAYNI-NHPT---DQIRVIETIAHPQYSNSTYANDIALVKLERSVIFNLNIQPICI-HLDATLGK 147
            |:..: :.|:   .:|.:||  .:|.|...   |||||:||:..:.|:..::|||: ..|..|..
Human   261 GSDKLGSFPSLAVAKIIIIE--FNPMYPKD---NDIALMKLQFPLTFSGTVRPICLPFFDEELTP 320

  Fly   148 QIRYYNAFGWGRTR--NAEQSDILQRIFVNRTNPMICH---LYLGMSPDPKQICATTDQG--DTC 205
            ....: ..|||.|:  ..:.||||.:..|...:...|:   .|.|...: |.:||...:|  |||
Human   321 ATPLW-IIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTE-KMMCAGIPEGGVDTC 383

  Fly   206 AGDSGGPLISKITYQGKNFDTQFGITSYGTRECNG---VGLYTDVSQYSGWIANIVRSKQDRSVV 267
            .|||||||:    ||...:.. .||.|:| ..|.|   .|:||.||.|..||.|:.:   ||::
Human   384 QGDSGGPLM----YQSDQWHV-VGIVSWG-YGCGGPSTPGVYTKVSAYLNWIYNVWK---DRTI- 438

  Fly   268 SRRSNGMFLYSDCTGDSIGSILMATIVGLQ--YSAKGVLITDRHVLTT 313
             :||        |.....|.::....|.|.  .||:     ..|.|||
Human   439 -QRS--------CNSPGTGLVIQQPAVPLMELRSAR-----HTHRLTT 472

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.