Protein Alignment CG43110 and PRSS2

DIOPT Version :10

• Sequence 1: NP_001246396.1
• Gene: CG43110 / 12798330
• FlyBaseID: FBgn0262570
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 75/267 - (28%)
• Similarity: 111/267 - (41%)
• Gaps: 75/267 - (28%)

  Fly    35 KIISGSNASQQSAQYMAGIFNTTHLLCGGTIIHEDFVLTVAHC-KST------------QTLFVR 86
            ||:.|....:.|..|...: |:.:..|||::|.|.:|::..|| ||.            ..:.||
Human    23 KIVGGYICEENSVPYQVSL-NSGYHFCGGSLISEQWVVSAGHCYKSAINSKLSGRGCEYHRIQVR 86

  Fly    87 LGAYNIN--HPTDQ-IRVIETIAHPQYSNSTYANDIALVKLERSVIFNLNIQPICI-------HL 141
            ||.:||.  ...:| |...:.|.||:|::.|..|||.|:||....:.|..:..|.:       ..
Human    87 LGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPTAPPAAGT 151

  Fly   142 DATLGKQIRYYNAFGWGRT--RNAEQSDILQRIFV--------------NRTNPMICHLYLGMSP 190
            ::.:.         |||.|  ..|:..|.||.:..              ..||.|.|..:|
Human   152 ESLIS---------GWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFL---- 203

  Fly   191 DPKQICATTDQG--DTCAGDSGGPLISKITYQGKNFDTQFGITS--YGTRECNGVGLYTDVSQYS 251
                      :|  |:|.||||||::|       |.:.| ||.|  ||..:.|..|:||.|..|.
Human   204 ----------EGGKDSCQGDSGGPVVS-------NGELQ-GIVSWGYGCAQKNRPGVYTKVYNYV 250

  Fly   252 GWIANIV 258
            .||.:.:
Human   251 DWIKDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	74/263 (28%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	74/263 (28%)