Protein Alignment CG43110 and PROC

DIOPT Version :10

• Sequence 1: NP_001246396.1
• Gene: CG43110 / 12798330
• FlyBaseID: FBgn0262570
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: XP_024308771.1
• Gene: PROC / 5624
• HGNCID: 9451
• Length: 556
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 85/303 - (28%)
• Similarity: 129/303 - (42%)
• Gaps: 65/303 - (21%)

  Fly    15 SCQLAYSM---------FLKQPCGK---------------------TPVPKIISGSNASQQSAQY 49
            ||...|.:         .:|.|||:                     ...|::|.|....:..:.:
Human   256 SCAPGYKLGDDLLQCHPAVKFPCGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPW 320

  Fly    50 MAGIFNT-THLLCGGTIIHEDFVLTVAHC-KSTQTLFVRLGAYNINHPTD---QIRVIETIAHPQ 109
            ...:.:: ..|.||..:||..:|||.||| ..::.|.||||.|::.....   .:.:.|...||.
Human   321 QVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPN 385

  Fly   110 YSNSTYANDIALVKLERSVIFNLNIQPICIHLDATLGKQIRYYN-------AFGWGRTRNAEQSD 167
            ||.||..|||||:.|.:....:..|.|||:. |:.|.:  |..|       ..|||...:.|:..
Human   386 YSKSTTDNDIALLHLAQPATLSQTIVPICLP-DSGLAE--RELNQAGQETLVTGWGYHSSREKEA 447

  Fly   168 ILQRIFVNRTN----PMI----CHLYLGMSPDPKQICA--TTDQGDTCAGDSGGPLISKITYQGK 222
            ...|.||  .|    |::    |...:........:||  ..|:.|.|.||||||:::  ::.|.
Human   448 KRNRTFV--LNFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACEGDSGGPMVA--SFHGT 508

  Fly   223 NFDTQFGITSYGTREC---NGVGLYTDVSQYSGWIANIVRSKQ 262
            .|  ..|:.|:| ..|   :..|:||.||:|..||...:|.|:
Human   509 WF--LVGLVSWG-EGCGLLHNYGVYTKVSRYLDWIHGHIRDKE 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	75/245 (31%)
PROC	XP_024308771.1	GLA	85..148	CDD:214503
		EGF_CA	162..193	CDD:238011
		FXa_inhibition	235..270	CDD:464251	3/13 (23%)
		Tryp_SPc	308..543	CDD:238113	75/244 (31%)