Protein Alignment CG43110 and KLK3

DIOPT Version :10

• Sequence 1: NP_001246396.1
• Gene: CG43110 / 12798330
• FlyBaseID: FBgn0262570
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 71/286 - (24%)
• Similarity: 110/286 - (38%)
• Gaps: 64/286 - (22%)

  Fly     1 MTYLFVWIFLCSLGSCQLAYSMFLKQPCGKTPVPKIISGSNASQQSAQYMAGIFNTTHLLCGGTI 65
            :|....||     |:..|..|             :|:.|....:.|..:...:.:....:|||.:
Human     8 LTLSVTWI-----GAAPLILS-------------RIVGGWECEKHSQPWQVLVASRGRAVCGGVL 54

  Fly    66 IHEDFVLTVAHCKSTQTLFVRLGAYNINHPTDQ---IRVIETIAHPQYSNSTYAN---------- 117
            :|..:|||.|||...::: :.||.:::.||.|.   .:|..:..||.|..|...|
Human    55 VHPQWVLTAAHCIRNKSV-ILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSS 118

  Fly   118 -DIALVKLERSV-------IFNLNIQPICIHLDATLGKQIRYYNAFGWGRTRNAE--QSDILQRI 172
             |:.|::|....       :.:|..|      :..||...   .|.|||.....|  ....||.:
Human   119 HDLMLLRLSEPAELTDAVKVMDLPTQ------EPALGTTC---YASGWGSIEPEEFLTPKKLQCV 174

  Fly   173 FVNRTNPMICHLYLGMSPDPKQICA--TTDQGDTCAGDSGGPLISKITYQGKNFDTQFGITSYGT 235
            .::..:..:|............:||  .|....||:|||||||:.....|        ||||:|:
Human   175 DLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQ--------GITSWGS 231

  Fly   236 REC---NGVGLYTDVSQYSGWIANIV 258
            ..|   ....|||.|..|..||.:.:
Human   232 EPCALPERPSLYTKVVHYRKWIKDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	65/248 (26%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	65/248 (26%)