Protein Alignment CG43110 and PRSS48

DIOPT Version :10

• Sequence 1: NP_001246396.1
• Gene: CG43110 / 12798330
• FlyBaseID: FBgn0262570
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001340540.1
• Gene: PRSS48 / 345062
• HGNCID: 24635
• Length: 346
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 97/370 - (26%)
• Similarity: 158/370 - (42%)
• Gaps: 95/370 - (25%)

  Fly    13 LGSCQLAYSMFLK---QPCGKTPV--PKIISGSNASQQSAQYMAGIFNTTHLLCGGTIIHEDFVL 72
            :|....|:::.|.   ..||: ||  .:::.|.:|:.....:...:....:.:|||:::.|..:|
Human     1 MGPAGCAFTLLLLLGISVCGQ-PVYSSRVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLIL 64

  Fly    73 TVAHC-KSTQTLF---VRLGAYNINHPTDQIR--VIETIAHPQYSNSTYANDIALVKLERSVIFN 131
            |.||| :.|.|.|   |.||:..:.....:::  |.:.:.||:|.::|  .|:||:||...|.|.
Human    65 TAAHCIQPTWTTFSYTVWLGSITVGDSRKRVKYYVSKIVIHPKYQDTT--ADVALLKLSSQVTFT 127

  Fly   132 LNIQPICIHLDATLGKQIR---YYNAFGWGRTRNAEQSD-----------ILQR----------- 171
            ..|.|||:   .::.||:.   :....|||:.:.:...|           |:.|
Human   128 SAILPICL---PSVTKQLAIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLYNPIG 189

  Fly   172 IFVNRTNPMICHLYLGMSPDPKQICA--TTDQGDTCAGDSGGPLISKITYQGKNFDTQFGITSYG 234
            ||:....|:|         ...:|||  |.:..|:|.|||||||...|    .....|.|:.|:|
Human   190 IFLPALEPVI---------KEDKICAGDTQNMKDSCKGDSGGPLSCHI----DGVWIQTGVVSWG 241

  Fly   235 TRECNG--VGLYTDVSQYSGWIANIVRSKQDRSVVSRRSNGMF--------------LYSDC--- 280
            . ||..  .|:||:|..|..||         .:.:||.:|..|              |...|
Human   242 L-ECGKSLPGVYTNVIYYQKWI---------NATISRANNLDFSDFLFPIVLLSLALLRPSCAFG 296

  Fly   281 --TGDSIGSI--LMATIVGLQ-----YSAKGVLITDRHVLTTADF 316
              |...:|::  .:|.|.|.:     :|.:|..:|...:||..||
Human   297 PNTIHRVGTVAEAVACIQGWEENAWRFSPRGRELTGEPLLTLGDF 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	72/255 (28%)
PRSS48	NP_001340540.1	Tryp_SPc	28..265	CDD:238113	72/264 (27%)