Protein Alignment CG43110 and HABP2

DIOPT Version :10

• Sequence 1: NP_001246396.1
• Gene: CG43110 / 12798330
• FlyBaseID: FBgn0262570
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_004123.1
• Gene: HABP2 / 3026
• HGNCID: 4798
• Length: 560
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 84/323 - (26%)
• Similarity: 129/323 - (39%)
• Gaps: 89/323 - (27%)

  Fly     7 WIFL-----------CSLGSC---QLAY------SMFLKQP----CGKT-----PVPKIISGSNA 42
            |.|:           |.:.:|   .:||      ....|.|    ||||     .:.:|..|..:
Human   256 WCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDSCGKTEIAERKIKRIYGGFKS 320

  Fly    43 SQQSAQYMAGIFNTTHL--------LCGGTIIHEDFVLTVAHCKSTQT--LFVRLGAYNI----- 92
            :.....:.|.:.::..|        .|||.:||..:|||.|||...:|  |.|.||..::
Human   321 TAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTDIKTRHLKVVLGDQDLKKEEF 385

  Fly    93 NHPTDQIRVIETIAHPQYSNSTYANDIALVKLE----RSVIFNLNIQPICI-----------HLD 142
            :..:.::..|...:|....:....|||||:||:    ...:.:..::.:|:           |:.
Human   386 HEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHCALESKYVKTVCLPDGSFPSGSECHIS 450

  Fly   143 ATLGKQIRYYNAFGWGRTRNAEQSDILQRIFVNRTNPMICH---LYLGMSPDPKQICATTDQ--- 201
                         |||.|...:.|..|....|......:|:   ||..|. |...|||...|
Human   451 -------------GWGVTETGKGSRQLLDAKVKLIANTLCNSRQLYDHMI-DDSMICAGNLQKPG 501

  Fly   202 GDTCAGDSGGPLISKI--TYQGKNFDTQFGITSYGTREC-NGVGLYTDVSQYSGWIANIVRSK 261
            .|||.|||||||..:.  ||.      .:||.|:|. || ...|:||.|:::..||...::|:
Human   502 QDTCQGDSGGPLTCEKDGTYY------VYGIVSWGL-ECGKRPGVYTQVTKFLNWIKATIKSE 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	71/259 (27%)
HABP2	NP_004123.1	EGF	77..106	CDD:394967
		KR	191..277	CDD:238056	3/20 (15%)
		Tryp_SPc	314..553	CDD:238113	71/259 (27%)