Protein Alignment CG43110 and TMPRSS12

DIOPT Version :10

• Sequence 1: NP_001246396.1
• Gene: CG43110 / 12798330
• FlyBaseID: FBgn0262570
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_872365.2
• Gene: TMPRSS12 / 283471
• HGNCID: 28779
• Length: 348
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 96/313 - (30%)
• Similarity: 139/313 - (44%)
• Gaps: 73/313 - (23%)

  Fly    26 QPCGKTPVPKIISGSNASQQSAQYMAGIFN------------TTHLLCGGTIIHEDFVLTVAHC- 77
            :.||..|:..::.||... ...:..||.:.            ..| :||||::.|.:|||.|||
Human    62 EDCGTAPLKDVLQGSRII-GGTEAQAGAWPWVVSLQIKYGRVLVH-VCGGTLVRERWVLTAAHCT 124

  Fly    78 --KSTQTLFVR-LGAYNIN--HP-TDQIRVIETIAHPQYSNSTYANDIALVKLERSVIFNLNIQP 136
              .|...::.. :|..||:  :| |.:|::...|.||.:...:|.|||||..|:::|.:|..|||
Human   125 KDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQP 189

  Fly   137 ICIHLDATLGKQIRYYNA----FGWGRTR-NAEQSDILQRIFVNRTNPMICH---LYLGMSPDPK 193
            ||:..|..   ||...|.    .|||||: ....::|||...|:..:..:|:   .|.|:.|: .
Human   190 ICLPFDVF---QILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPN-T 250

  Fly   194 QICATTDQG--DTCAGDSGGPLISKITYQGKNFDTQFGITSYGTRECNG---VGLYTDVSQYSGW 253
            ..||..:.|  |||.|||||||:..:....:.|  ..|||||| ..|..   .|:|...|.|..|
Human   251 SFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFF--VMGITSYG-HGCGRRGFPGVYIGPSFYQKW 312

  Fly   254 IA--------------NIVRSKQDRSVVSRRSNGMFLYSDCTGDSIGSILMAT 292
            :.              ||:|             |..|.:.|.     .||:||
Human   313 LTEHFFHASTQGILTINILR-------------GQILIALCF-----VILLAT 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	83/266 (31%)
TMPRSS12	NP_872365.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46
		Tryp_SPc	78..316	CDD:238113	81/246 (33%)