Protein Alignment CG43110 and KLK13

DIOPT Version :10

• Sequence 1: NP_001246396.1
• Gene: CG43110 / 12798330
• FlyBaseID: FBgn0262570
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_056411.1
• Gene: KLK13 / 26085
• HGNCID: 6361
• Length: 277
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 86/288 - (29%)
• Similarity: 123/288 - (42%)
• Gaps: 59/288 - (20%)

  Fly     6 VWIFLCSLGSCQLAYSMFLKQPCGKTP--------VPKIISGSNASQQSAQYMAGIFNTTHLLCG 62
            :|.....:.|..||.|..:.|...|..        :|   .|......|..:.|.:.....||||
Human     1 MWPLALVIASLTLALSGGVSQESSKVLNTNGTSGFLP---GGYTCFPHSQPWQAALLVQGRLLCG 62

  Fly    63 GTIIHEDFVLTVAHCKSTQTLFVRLGAYNIN--HPTDQIR-VIETIAHPQYSNS-TYAN---DIA 120
            |.::|..:|||.|||.. :.|.|.||.:.:.  ...:|:| |:.:|.||:|..| |:.|   ||.
Human    63 GVLVHPKWVLTAAHCLK-EGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLNHDHDIM 126

  Fly   121 LVKLERSVIFNLNIQ--PICIHLDATLGKQIRYYNAFGWGRTRNAEQSDILQRIFVNRTNPMIC- 182
            |::|:..|.....||  |:..:...|.|...|   ..|||.|.:.:         ||....:.|
Human   127 LLELQSPVQLTGYIQTLPLSHNNRLTPGTTCR---VSGWGTTTSPQ---------VNYPKTLQCA 179

  Fly   183 -----------HLYLGMSPDPKQICATTDQG--DTCAGDSGGPLISKITYQGKNFDTQFGITSYG 234
                       .:|.|...| ..:||.|.:|  |:|.|||||||:..        .|.:||.|:|
Human   180 NIQLRSDEECRQVYPGKITD-NMLCAGTKEGGKDSCEGDSGGPLVCN--------RTLYGIVSWG 235

  Fly   235 TREC---NGVGLYTDVSQYSGWIANIVR 259
            ...|   :..|:||.||:|..||...:|
Human   236 DFPCGQPDRPGVYTRVSRYVLWIRETIR 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	77/246 (31%)
KLK13	NP_056411.1	Tryp_SPc	38..261	CDD:238113	77/244 (32%)